OBJECTIVE To investigate the interobserver and test-retest reproducibility of T1ρ and T2 measurements of lumbar intervertebral discs using 3T magnetic resonance imaging (MRI). MATERIALS AND METHODS This study included a total of 51 volunteers (female, 26; male, 25; mean age, 54 ± 16.3 years) who underwent lumbar spine MRI with a 3.0 T scanner. Amongst these subjects, 40 underwent repeat T1ρ a...

OBJECTIVE In vivo Corneal Confocal Microscopy (IVCCM) is a validated, non-invasive test for diabetic sensorimotor polyneuropathy (DSP) detection, but its utility is limited by the image analysis time and expertise required. We aimed to determine the inter- and intra-observer reproducibility of a novel automated analysis program compared to manual analysis. METHODS In a cross-sectional diagnos...

BACKGROUND Although facial cleanliness is part of the SAFE strategy for trachoma there is controversy over the reliability of measuring a clean face. A child's face with no ocular and nasal discharge is clean and the endpoint of interest, regardless of the number of times it must be washed to achieve that endpoint. The issue of reliability rests on the reproducibility of graders to assess a cle...

In diagnostic and research reports as well as text-books of human and veterinary pathology repeatability, reproducibility, inter- and intra-observer variation are mentioned rarely as a problem in preparing diagnosis from macroscopic and/or microscopic samples and discussed inconsistently. However, optimal care and restoration of health for a patient are dependent on reliability of diagnosis, th...

Abstract Funding Acknowledgements Type of funding sources: None. Background The use 2D and 4D during stress echocardiography to undertake complex measures in patients like with repaired TOF is challenging the validity these not known yet. Methods For test-retest variability, 20 no or mild pulmonary regurgitation were selected randomly underwent a cardiopulmonary exercise test (CPET) echocardiog...

OBJECTIVE To assess the reproducibility of a novel scoring system that we have developed for the objective assessment of acute inflammatory change in JDM. This system defines markers of inflammatory change in four muscle groups and the surrounding soft tissues. METHODS Forty-eight children (33 girls) underwent retrospective assessment of their MRI studies by two musculoskeletal paediatric rad...

Intra-observer and inter-study reproducibility of brachial artery flow-mediated dilatation (FMD) and glyceryl trintrate (GTN)-mediated dilatation by CMR at 3Tesla were assessed. Coefficients of variation (CoV) were calculated using the root mean square method. The intra-observer CoV, assessed in 15 subjects, was 15% for both FMD and GTN response. The inter-study CoV, assessed in 17 subjects, wa...

AIMS Although the coronary artery vessel wall can be imaged non-invasively using magnetic resonance imaging (MRI), the in vivo reproducibility of wall thickness measures has not been previously investigated. Using a refined magnetization preparation scheme, we sought to assess the reproducibility of three-dimensional (3D) free-breathing black-blood coronary MRI in vivo. METHODS AND RESULTS MR...

Observer error in the assessment of marrow hypocellularity was studied by examining histological sections from 37 mice having normal or reduced marrow cellularity and comparing the estimated cellularity with a previously measured value. For marrows or mild or moderately reduced cellularity the subjective estimate of cellularity was almost valueless both in terms of accuracy and reproducibility....

The increasing importance of ultrasound in obstetrical practice requires a sound knowledge of the technique and of the reproducibility and accuracy of the measurements. In most obstetrical clinics, scanning are not always performed by the same technician and therefore the lack of Information about the errors in measurement of the different observers or of one observer may lead to inaccurate pro...