The cache decisions of scatter-hoarding animals are influenced by a number of factors, including satiety, food quality, number of competitors, and the risk of predation and pilferage. However, it is unknown how animals assess these variables. We investigated this process experimentally in free-ranging fox squirrels (Sciurus niger) by measuring the effects of nut characteristics and social conte...

Purpose: Because the nongenotoxic inhibitor of the p53/MDM2 interactions Nutlin-3 has shown promising in vitro therapeutic activity against a variety of p53 cancer cells, in this study we evaluated an innovative strategy able to specifically target Nutlin-3 toward CD20þ malignant cells. Experimental Design: The cytotoxic effects of Nutlin-3 encapsulated into poly(lactide-co-glycolide) nanoparti...

UNLABELLED NUT midline carcinoma (NMC) is an aggressive subtype of squamous cell carcinoma that typically harbors BRD4/3-NUT fusion oncoproteins that block differentiation and maintain tumor growth. In 20% of cases, NUT is fused to uncharacterized non-BRD gene(s). We established a new patient-derived NMC cell line (1221) and demonstrated that it harbors a novel NSD3-NUT fusion oncogene. We find...

OBJECTIVE To determine the effects of soy consumption on markers of inflammation and endothelial function in postmenopausal women with the metabolic syndrome. RESEARCH DESIGN AND METHODS This randomized cross-over clinical trial included 42 postmenopausal women with the metabolic syndrome. Participants were randomly assigned to consume a control diet (Dietary Approaches to Stop Hypertension [...

Background: Epidemiological studies have consistently associated nut consumption with reduced risk for coronary heart disease. Subsequently, many dietary intervention trials investigated the effects of nut consumption on blood lipid levels. The objectives of this study were to estimate the effects of nut consumption on blood lipid levels and to examine whether different factors modify the effects.

BACKGROUND The work force in industries are at risk of developing unduly high rates of health and behaviour related problems including abuse of alcohol, betel nut and cigarette (alcohol, betel nut and cigarette consumption). This study describes the relationships between alcohol, betel nut and cigarette consumption and health promoting behaviour among industrial workers. MATERIALS AND METHODS...

ago [12]; however, the standard error is 65,000 years at these sample sizes. The MLS sequence documents a greater diversity among the European Neandertals than previously estimated. In particular, the MLS and MEZ sequences appear separated from a cluster of sequences from Germany and Croatia. All sequences in the cluster share two derived alleles, 16078G and 16154C. The analysis of Neandertal g...

The pomological properties and nutritional values of walnuts vary according to the cultivars and ecological conditions. This study aims to determine some pomological properties and fatty acid compositions of some domestic ('Bilecik', 'Maraş 12', 'Maraş 18', 'Şebin', 'Şen1', 'Şen 2') and foreign walnut cultivars (‘Chandler', 'Fernette', 'Fernor', 'Howard', 'Pedro', 'Serr') grown in Bursa (northw...

This article summarizes the main conclusions drawn from a conference on the health effects of nut consumption and identifies priority areas for future research. Individuals with higher intakes of nuts generally have higher intakes of many beneficial dietary constituents. More information is needed on nut composition, the bioavailability of nutrients, and other bioactive constituents. Better met...

NUT midline carcinoma (NMC) is an aggressive subset of squamous cell carcinoma, genetically defined by rearrangement of the NUT gene. The rearrangements most often take the form of BRD4-NUT fusions, and in a minority of cases, BRD3-NUT or NUT-variant fusions. The simple karyotypes of NMCs, in contrast to the complex ones of typical squamous cell carcinoma, suggest an alternate, genetic shortcut...