2002 Winstock A. Areca nut-abuse liability, dependence and public health. Addict Biol 2002; 7:133± 8. Williams S, Malik A, Chowdhury S, Chauhan S. Socio-cultural aspects of areca nut use. Addict Biol 2002;7:147± 54. Warnakulasuriya S. Areca nut use following migration and its consequences. Addict Biol 2002;7:127± 32. Trivedy CR, Craig G, Warnakulasuriya S. The oral health consequences of chewin...

PURPOSE Because the nongenotoxic inhibitor of the p53/MDM2 interactions Nutlin-3 has shown promising in vitro therapeutic activity against a variety of p53(wild-type) cancer cells, in this study we evaluated an innovative strategy able to specifically target Nutlin-3 toward CD20(+) malignant cells. EXPERIMENTAL DESIGN The cytotoxic effects of Nutlin-3 encapsulated into poly(lactide-co-glycoli...

INTRODUCTION Areca nut chewing has been shown to increase the risk of cardiovascular disease, but its association with erectile dysfunction (ED) has not been investigated. AIM To investigate the association between areca nut chewing and risk of ED. METHODS Consecutive men at public health centers for oral malignancy screening or health checkup were invited to complete a questionnaire. MAI...

Studies were conducted to develop an appropriate household/small scale enterprise level technique for the production of bambara-nut-fortified fermented maize dough or meal by comparing different treatments, processing methods and fortification levels. The effect of fortification of maize based traditional foods with legume protein, bambara-nut at 0%. 10% and 20% replacement levels, on the rate ...

The cache decisions of scatter-hoarding animals are influenced by a number of factors, including satiety, food quality, number of competitors, and the risk of predation and pilferage. However, it is unknown how animals assess these variables. We investigated this process experimentally in free-ranging fox squirrels (Sciurus niger) by measuring the effects of nut characteristics and social conte...

Purpose: Because the nongenotoxic inhibitor of the p53/MDM2 interactions Nutlin-3 has shown promising in vitro therapeutic activity against a variety of p53 cancer cells, in this study we evaluated an innovative strategy able to specifically target Nutlin-3 toward CD20þ malignant cells. Experimental Design: The cytotoxic effects of Nutlin-3 encapsulated into poly(lactide-co-glycolide) nanoparti...

The security dynamics described by the Black-Scholes equation with price-dependent variance can be approximated as a damped discrete-time hopping process on a recombining binomial tree. In a previous working paper, such a nonuniform tree was explicitly constructed in terms of the continuous-time variance. The present note outlines how the previous procedure could be extended to multifactor Blac...

UNLABELLED NUT midline carcinoma (NMC) is an aggressive subtype of squamous cell carcinoma that typically harbors BRD4/3-NUT fusion oncoproteins that block differentiation and maintain tumor growth. In 20% of cases, NUT is fused to uncharacterized non-BRD gene(s). We established a new patient-derived NMC cell line (1221) and demonstrated that it harbors a novel NSD3-NUT fusion oncogene. We find...

OBJECTIVE To determine the effects of soy consumption on markers of inflammation and endothelial function in postmenopausal women with the metabolic syndrome. RESEARCH DESIGN AND METHODS This randomized cross-over clinical trial included 42 postmenopausal women with the metabolic syndrome. Participants were randomly assigned to consume a control diet (Dietary Approaches to Stop Hypertension [...

Background: Epidemiological studies have consistently associated nut consumption with reduced risk for coronary heart disease. Subsequently, many dietary intervention trials investigated the effects of nut consumption on blood lipid levels. The objectives of this study were to estimate the effects of nut consumption on blood lipid levels and to examine whether different factors modify the effects.