Cord blood is widely used as surrogate tissue in epigenome-wide association studies of prenatal conditions. Cell type composition variation across samples can be an important confounder of epigenome-wide association studies in blood that constitute a mixture of cells. We evaluated a newly developed cord blood reference panel to impute cell type composition from DNA methylation levels, including...

Currie, Suzanne, Bruce L. Tufts, and Christopher D. Moyes. Influence of bioenergetic stress on heat shock protein gene expression in nucleated red blood cells of fish. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R990–R996, 1999.—The physiological and biochemical signals that induce stress protein (HSP) synthesis remain conjectural. In this study, we used the nucleated red bl...

The D antigen content of nucleated red cell precursors in human bone marrow was estimated using autoradiography and 125I-anti-D. D antigen first appeared in the pronormoblast, and the quantity of antigen progressively increased during red cell maturation. Maximal anti-D binding occurred on mature red blood cells. Pronormoblasts, basophilic normoblasts, polychromatophilic normoblasts, and orthoc...

1. The respiration of the reticulocytes of the rabbit has been measured during the period of an anemia produced by phenylhydrazine. Though the respiration increased greatly during the phase of regeneration, the oxygen consumption per billion reticulocytes throughout the period remained approximately the same. 2. The respiration of the reticulocytes was affected by changes in the reaction of the...

Assessment of the condition a patient with coronavirus infection is an urgent problem in clinical practice. The parameter ’nucleated erythrocytes’ blood test can be used practice as marker hypoxia case lung damage, since it objectively reflects consequences acute hypoxic stress patient’s body.

©Copyright 2017 by Turkish Society of Hematology Turkish Journal of Hematology, Published by Galenos Publishing House An 84-year-old male diagnosed with primary myelofibrosis based on WHO grade 2-3 fibrosis (Figure 1) and the presence of the JAK2-V617F mutation was treated with supportive care. During 2 years of follow-up, his hemoglobin level was maintained at approximately 6.5 mmol/L and plat...

Nucleated red blood cells (NRBCs) are premature erythrocyte precursors that reside in the bone marrow of humans all ages as an element erythropoiesis. They rarely present healthy adults’ circulatory systems but can be found circulating fetuses and neonates. An NRBC count is a cost-effective laboratory test currently used everyday clinical practice; it mostly diagnosis hematological diseases/dis...