نتایج جستجو برای: nuclear factor kappa

تعداد نتایج: 1054869  

2018
Weina Cao Hongtao Huang Tianyu Xia Chenlong Liu Saeed Muhammad Chao Sun

Citation: Cao W, Huang H, Xia T, Liu C, Muhammad S and Sun C (2018) Homeobox a5 Promotes White Adipose Tissue Browning Through Inhibition of the Tenascin C/Toll-Like Receptor 4/Nuclear Factor Kappa B Inflammatory Signaling in Mice. Front. Immunol. 9:647. doi: 10.3389/fimmu.2018.00647 homeobox a5 Promotes White adipose Tissue Browning Through inhibition of the Tenascin c/Toll-like receptor 4/nuc...

Objective(s): This study aims to investigate the pathogenicity and possible mechanisms of S100A9 function in mice models of scleroderma. Materials and Methods: The content of S100A9 in the skin tissues of mice with scleroderma was determined. Different concentrations of bleomycin (BLM) and S100A9 were subcutaneously injected into the backs of mice simultaneously, and then pathological changes i...

Journal: :The Biochemical journal 2003
Christina Widén Jan-Ake Gustafsson Ann-Charlotte Wikström

The glucocorticoid receptor (GR) acts as an anti-inflammatory factor. To a large extent, this activity is exerted by the interference of pro-inflammatory nuclear factor kappa B (NF-kappa B) activity. In their respective inactive forms, both GR and NF-kappa B reside in the cytoplasm and translocate to the nucleus on relevant stimulation. Previously, p65, a component of the NF-kappa B complex, an...

Journal: :The Journal of clinical investigation 1992
P A Kaufman J B Weinberg W C Greene

The nuclear factor (NF)-kappa B transcription factor system is composed of at least four inducible nucleoprotein adducts termed p50, p55 (NF-kappa B p50), p75 (NF-kappa B p65), and p85 (c-Rel). These proteins are expressed in the nuclei of activated T cells in a distinctly biphasic fashion, with p55 and p75 induction occurring within minutes whereas the induction of p50 and p85 occurs after sev...

2014
Justine M Betzu Neel Jasani Bina Desai Vikas Sehdev

PI3K: Phosphoinositide 3-Kinase; Akt or PKB: Protein Kinase B; cAMP: Cyclic Adenosine Monophosphate; ATP: Adenosine Triphosphate; NFκB: Nuclear Factor Kappa B; APC: Adenomatous Polyposis Coli; GEO: Gene Expression Omnibus; GI: Gastrointestinal; EGFR: Epidermal Growth Factor Receptor; HER2: Human Epidermal Growth Factor Receptor 2; AURKA: Aurora kinase A; IP3: Inositol Triphosphate; PLC: Phospho...

2018
Leyla Acar Nazan Atalan E. Hande Karagedik Arzu Ergen

BACKGROUND The humoral system is activated and various cytokines are released due to infections in tissues and traumatic damage. Nuclear factor-kappa B dimers are encoded by nuclear factor-kappa B genes and regulate transcription of several crucial proteins of inflammation such as tumour necrosis factor-alpha. AIMS To investigate the possible effect of polymorphisms on tumour necrosis factor-...

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