The H-NOX (Heme-Nitric oxide/OXygen binding) family of diatomic gas sensing hemoproteins has attracted great interest. Soluble guanylate cyclase (sGC), the well-characterized eukaryotic nitric oxide (NO) sensor is an H-NOX family member. When NO binds sGC at the ferrous histidine-ligated protoporphyrin-IX, the proximal histidine ligand dissociates, resulting in a 5-coordinate (5c) complex; form...

Our current understanding of secondary organic aerosol (SOA) formation is limited by our knowledge of gaseous secondary organics involved in gas/particle partitioning. The objective of this study is to explore (i) the potential for products of multiple oxidation steps contributing to SOA, and (ii) the evolution of the SOA/VOC/NOx system. We developed an explicit model based on the coupling of d...

The study by Henze et al. ”Global modeling of secondary organic aerosol formation from aromatic hydrocarbons: Highvs low-yield pathways” investigates the global relevance of recent simulation chamber results that parameterize the NOx dependence of SOA yields from benzene, toluene and m-xylene, by Ng et al. (2007). The paper is generally well written, and presents the results on the NOx dependen...

The effects of 26 individual volatile organic compounds (VOCs) on ozone formation, NO oxidation, and OH radical levels were measured by adding them to reactive organic gas (ROG) NOx air environmental chamber irradiations representing a simplified model photochemical smog system. These experiments had relatively low ROG/NOx ratios to represent conditions where ozone formation is most sensitive t...

Throughout Europe the summer of 2003 was exceptionally warm, especially July and August. The European Environment Agency (EEA) reported several ozone episodes, mainly in the first half of August. These episodes were exceptionally long-lasting, spatially extensive, and associated to high temperatures. In this paper, the 10–15 August 2003 ozone pollution event has been analyzed using meteorologic...

This paper presents an excellent review of the theory of solid fuel combustion and NOx formation and control in the context of solid waste combustion. After pointing out that most research on NOx formation from solid fuels has been done on coal, the authors correctly point out that the while the basic principles of fuel and thermal NOx formation are well understood and permit NOx reductions in ...

Methamphetamine (METH) is a drug of abuse with neurotoxic and vascular effects that may be mediated by reactive oxygen species (ROS). However, potential sources of METH-induced generation of ROS are not fully understood. This study is focused on the role of NAD(P)H oxidase (NOX) in METH-induced dysfunction of brain endothelial cells. Treatment with METH induced a time-dependent increase in phos...

NOx emissions in n-heptane/air partially premixed flames (PPFs) in a counter-flow configuration have been investigated. The flame is computed using a detailed mechanism that combines the Held’s mechanism for n-heptane and the Li and Williams’ mechanism for NOx. The combined mechanism contains 54 species and 327 reactions. Based on a detailed analysis, dominant mechanisms responsible for NOx for...