نتایج جستجو برای: novoseven

تعداد نتایج: 115  

Journal: :BJA: British Journal of Anaesthesia 2008
D. Viuff B. Lauritzen A. E. Pusateri S. Andersen R. Rojkjaer P. I. Johansson

BACKGROUND A range of plasma volume expanders is used clinically, often in settings where haemostasis may already be impaired. The haemostatic agent, recombinant activated factor VII (rFVIIa, NovoSeven), may be used to improve haemostasis but potential interactions with different volume expanders are poorly understood. METHODS Clot formation was measured by thromboelastography (TEG) using blo...

2007
Sandra Magnetti Karl A. Matuszewski

INTRODUCTION Recombinant activated coagulation factor VII (rFVIIa) is a hemostatic agent developed by Novo Nordisk Pharmaceuticals, Inc., under the trademark NovoSeven. It is a recombinant DNA preparation of a naturally occurring protease, activated blood coagulation factor VII. It is nearly identical to plasmaderived activated factor VII in its pharmacokinetics, structure, and function. The FD...

2010
Pär I Johansson Sisse R Ostrowski

BACKGROUND Recombinant activated factor VII (rFVIIa, NovoSeven) was introduced in 1996 for the treatment of hemophilic patients with antibodies against coagulation factor VIII or IX. OBJECTIVE To review the evidence supporting the use of rFVIIa for the treatment of patients with congenital bleeding disorders. PATIENTS AND METHODS English-language databases were searched in September 2009 fo...

2016
Mina Golestani Peyman Eshghi Hamid Reza Rasekh Abdoll Majid Cheraghali Jamshid Salamzadeh Majid Naderi Mohammad Reza Managhchi Hamid Hoorfar Gholam Reza Toogeh Ali Imani Mohammad Taghi Khodayari Behnaz Habibpanah Razieh Hantooshzadeh

Nowadays, bypassing agents such as recombinant activated factor VII (rFVIIa) and activated prothrombin complex concentrates (aPCC) are used to treat bleeding episodes in the Hemophilia patients with inhibitors. AryoSeven® is an Iranian biogeneric rFVIIa with homogeneity of efficacy and the nature to NovoSeven in a comparative trial. The current clinical trial aimed to evaluate the cost-effectiv...

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