We measured daily excretion rates for urinary protein and the ratios of urinary protein to creatinine in 24-h urines and in untimed urines in 60 healthy adults, 30 patients with kidney disease, and 22 kidney-transplant recipients. The ratios for urinary protein/creatinine, mg/g, in untimed urines and in 24-h urines from the same subjects were closely correlated (r = 0.97) for rates of protein e...

Background: Early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. Angiotensin converting enzyme inhibitors (ACEIs) and antagonists of angiotensin II receptors type I (ARBs) are currently used as first-line treatment for albuminuria in these patients. The present study was conducted to assess the efficacy of addition of spi...

BACKGROUND AND OBJECTIVES There are no studies associating ventilatory mode effects on renal repercussions during pneumoperitoneum. This study aimed at evaluating pneumoperitoneum-induced renal hemodynamics and function changes in dogs under volume and pressure controlled ventilation. METHODS This study involved 16 dogs anesthetized with sodium thiopental and fentanyl, which were divided in t...

OBJECTIVE Urinary netrin-1 is a new marker to demonstrate early tubular damage. The aim of this study was to determine whether urinary netrin-1 is increased in obese children. METHODS A total of 68 normoalbuminuric and normotensive obese patients and 65 controls were included in the study. Urine samples were collected for assessment of urinary phosphorus, sodium, potassium, creatinine, albumi...

Diabetes mellitus is the commonest cause of ESRD worldwide and third most common cause in Nigeria. Recent reports from Nigeria indicate the prevalence of diabetic nephropathy as an aetiology of ESRD is increasing necessitating early diagnosis of diabetic nephropathy. We measured the urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG), NAG/creatinine ratio, urinary protein-creatinine rati...

BACKGROUND Hypercalciuria is one of the most common causes of unexplained isolated hematuria. The diagnostic methods for hypercalciuria have not yet been standardized. The aim of this study was to assess whether random urinary calcium/creatinine ratio could be used as a screening tool for hypercalciuria in children with hematuria. METHODS This prospective study included 264 children with prim...

Introduction: Development of peak bone mass and premenopausal bone loss is determined by the menstrual status of a women. Objective of this study was to determine the association of urinary calcium and phosphate with bone loss in post-menopausal women. This study is cross sectional. It was carried out in the Department of Biochemistry, Basic Medical Sciences Institute, Jinnah Postgraduate Medic...

background: early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. angiotensin converting enzyme inhibitors (aceis) and antagonists of angiotensin ii receptors type i (arbs) are currently used as first-line treatment for albuminuria in these patients. the present study was conducted to assess the efficacy of addition of spi...

OBJECTIVES To assess urinary NAG/ urinary creatinine (NAG/ Cr) ratio in patients with urological abnormalities (normal and abnormal ultrasonography) and compare it with normal healthy children. METHODS A prospective study was conducted from November 2012 to April 2013. Urine samples were collected from 70 patients with various urological abnormalities, and from 40 healthy control groups, thei...