نتایج جستجو برای: noninvasive biomarkers

تعداد نتایج: 131939  

Journal: :Journal of Postgenomics Drug & Biomarker Development 2011

2012
Mikako Obika Hirofumi Noguchi

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of elevated liver function tests results, after the commonly investigated causes have been excluded, and frequently coexists with type 2 diabetes mellitus (T2DM) because the conditions have common risk factors. As both T2DM and NAFLD are related to adverse outcomes of the other, diagnosis and valuation of fatty liver is an import...

Journal: :Nature Reviews Gastroenterology & Hepatology 2011

2012
Yan Liang Samantha M. Yeligar Lou Ann S. Brown

Exhaled breath condensate (EBC) has been increasingly studied as a noninvasive research method for sampling the alveolar and airway space and is recognized as a promising source of biomarkers of lung diseases. Substances measured in EBC include oxidative stress and inflammatory mediators, such as arachidonic acid derivatives, reactive oxygen/nitrogen species, reduced and oxidized glutathione, a...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2016
Angel Diaz-Lagares Jesus Mendez-Gonzalez David Hervas Maria Saigi Maria J Pajares Diana Garcia Ana B Crujerias Ruben Pio Luis M Montuenga Javier Zulueta Ernest Nadal Antoni Rosell Manel Esteller Juan Sandoval

PURPOSE Lung cancer remains as the leading cause of cancer-related death worldwide, mainly due to late diagnosis. Cytology is the gold-standard method for lung cancer diagnosis in minimally invasive respiratory samples, despite its low sensitivity. We aimed to identify epigenetic biomarkers with clinical utility for cancer diagnosis in minimally/noninvasive specimens to improve accuracy of curr...

2016
Bang-Fen Zhou Jin-Huan Wei Zhen-Hua Chen Pei Dong Ying-Rong Lai Yong Fang Hui-Ming Jiang Jun Lu Fang-Jian Zhou Dan Xie Jun-Hang Luo Wei Chen

We previously demonstrated that amplified in breast cancer 1 (AIB1) and eukaryotic initiation factor 2 (EIF5A2) overexpression was an independent predictor of poor clinical outcomes for patients with bladder cancer (BCa). In this study, we evaluated the usefulness of AIB1 and EIF5A2 alone and in combination with nuclear matrix protein 22 (NMP22) as noninvasive diagnostic tests for BCa. Using ur...

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