a 78-year-old woman presented with epigastric pain following the use of non-steroidal anti-inflammatory drugs (nsaids) for joint pain relief. she underwent ugi endoscopy. during ugi endoscopy she suffered from severe retching despite the use of sedatives. at 6 hours after the procedure, she developed raccoon eyes with chemosis. biopsy from the gastrointestinal (gi) mucosa revealed amyloidosis.

Although non-steroidal anti-inflammatory drugs (NSAIDs) and opioid compounds are widely used in the releif of pain, they are not always useful due to their side effects. It seems necessary to search for newer analgesic compounds. Therefore, we decided to study the analgesic effects of this plant. For extraction, percolation method was used and different weights of dried extract were dissolved i...

A 34 year old female developed acute pancreatitis after commencing diclofenac for a painful arthropathy. The possible role of prostaglandin inhibition in non-steroidal analgesic drug-induced pancreatitis is discussed and the suggestion is made that serum amylase should be measured in patients who develop abdominal pain, following ingestion of non-steroidal anti-inflammatory

Although non-steroidal anti-inflammatory drugs (NSAIDs) and opioid compounds are widely used in the releif of pain, they are not always useful due to their side effects. It seems necessary to search for newer analgesic compounds. Therefore, we decided to study the analgesic effects of this plant. For extraction, percolation method was used and different weights of dried extract were dissolved i...

Emphysematous gastritis is rare infection of the gastric wall associated with high mortality. Damage mucosal barrier and bacterial translocation can lead to emphysematous gastritis. Non-steroidal anti-inflammatory drugs use one etiological factors. Due mortality rates, early diagnosis treatment important. Patients are presenting emergency departments generally non-specific acute abdominal signs...

A case-control study was performed to determine whether aspirin confers a similar risk of bleeding from gastric or duodenal ulcers in the elderly as non-aspirin, non-steroidal anti-inflammatory drugs. The intake of analgesics in 230 patients with bleeding ulcers aged 60 and over and in hospital and community controls matched for age and sex was examined. Those who had taken aspirin were between...

The chiral pool amino acids have been utilized for the construction of steroidal and non-steroidal architectures in the quest for steroidomimetics. Chirality derived from amino acid-based architectures provides new and easy to incorporate chiral chemical space, which is otherwise very difficult to introduce and comprised of several synthetic steps for asymmetric steroids. The different and exci...

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Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel injuries caused by NSAIDs, and new endoscopic techniques such as capsule endoscopy and double balloon endoscopy can help in detecting such inj...