Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterised by persistent inflammation of synovial joints, often leading to joint destruction and disability. The major goals of treatment are to relieve pain, reduce inflammation, slow down or stop joint damage, prevent disability, and preserve or improve the patient's sense of wellbeing and ability to function.

Abstract Even after decades of intensive research, assessing rock slope stability remains a challenge. One reason for this is the spatial variability bridges (RBs) related to non-persistent, pre-existing geological structures, especially as detection RBs generally limited post-failure period. Thus, identification and classification their inclusion in numerical studies are demanding, yet essenti...

Introduction Juvenile idiopathic arthritis (JIA) is the most common chronic pediatric rheumatic disease, affecting 4 of every 1,000 children worldwide. It may cause joint damage, persistent pain and retardation of normal growth, which eventually may lead to long-term disability and decreased quality of life. Treatment aims disease control and induction of remission, preventing joint damage and ...

background: generalized joint hyper mobility predisposes some individuals to a wide variety of musculoskeletal complaints. given the critical role of scapular position in function of shoulder, the aim of this study was to compare scapular position between persons with and without general joint hyper mobility. methods: by nonprobability sampling 30 hyper mobile persons at average of 22.86 ±2.77 ...

Persistent postsurgical pain is a prevalent but underacknowledged condition. The aim of this study was to assess the prevalence, sensory qualities, and postoperative determinants of persistent pain at 3 to 4years after total knee replacement (TKR) and total hip replacement (THR). Patients completed a questionnaire with included the Western Ontario and McMaster Universities Index of Osteoarthrit...

Background/objective: Despite the present routine treatment of septic arthritis with antibacterial agents, articular damage is persistent and frequently leads to loss of joint function.  The aim of this study was to assess the effect of intra-articular corticosteroids added to systemic antibiotics in the treatment of experimental staphylococcal knee joint infection in rabbits. Methods: Thirty r...

Juvenile idiopathic arthritis (JIA) includes several forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in pain, joint deformity, and growth im- pairment, with possible persistent active arthritis into adulthood. Prior treatment involved non-specific agents, several with significant adverse effects. The recent use...