The evolution of multi-antibiotic resistance in bacterial pathogens, often resulting from de novo mutations, is creating a public health crisis. Phages show promise for combating antibiotic-resistant bacteria, the efficacy of which, however, may also be limited by resistance evolution. Here, we suggest that phages may be used as supplements to antibiotics in treating initially sensitive bacteri...

Significant evidence supports the effectiveness and safety of several complementary or integrative treatment approaches to common primary care problems. Acupuncture is effective in the management of chronic low back pain. Mind-body interventions such as cognitive behavior therapy, yoga, tai chi, qi gong, and music therapy may be helpful for treating insomnia. Exercise can reduce anxiety symptom...

The weaning time is a crucial period in the management of piglets. The risk of development of post-weaning diarrhoea (PWD) in piglets is high. PWD is the cause of serious economic losses in pig herds. Since 2006, the use of antibiotic growth promoters for prevention of diarrhoeal diseases in piglets has been banned. This measure also led to the investigation of alternative suitable feed supplem...

Commercial poultry production is ranked among the highest source of animal protein in the world. Microbial infections caused by bacteria (Salmonella, Clostridium perfringes) and parasites particularly Eimeria has continued to challenge the poultry industry. Antibiotic Growth Promoters (AGP) have been traditionally used to counter microbial infections in poultry. But due to public health concern...

During antibiotic drug development, media are frequently spiked with either serum/plasma or protein supplements to evaluate the effect of protein binding. Usually, previously reported serum or plasma protein binding values are applied in the analysis. The aim of this study was to evaluate this approach by experimentally measuring free, unbound concentrations for antibiotics with reportedly high...

BACKGROUND World Health Organization recommends a standard daily oral dose of iron and folic acid (IFA) supplements throughout pregnancy to begin as early as possible. The aim of the present study was to determine the prevalence of use of antenatal IFA supplements, and the socio-demographic factors associated with the non-use of antenatal IFA supplements from 14 selected districts in Pakistan. ...

Herbal medicines or natural products and plant extract may exhibit promising alternatives supplements for chemotherapy antibiotic therapy. The aim of the study is to evaluate therapeutic value phytoconstituents whole plant, Nepeta distans. methanol contains four known compounds, namely, oleanolic acid, ursolic β-sitosterol, stigmasterol. structures these compounds were confirmed with help NMR m...

Understanding potential provocations of haemorrhage is important in a range of clinical settings, and particularly for people with abnormal vasculature. Patients with hereditary haemorrhagic telangiectasia (HHT) can report haemorrhage from nasal telangiectasia in real time, and suggested dietary factors may precipitate nosebleeds. To examine further, nosebleed severity, dietary supplement use, ...

as one in which the woman (a) developed a temperature of 37.8'C or more, (b) had some local evidence of infection of the genital tract, and (c) was treated with an antibacterial drug. On this basis four of the women in the I.U.C.D. group (none of whom was using a Dalkon shield) and two in the "other methods" group suffered a septic abortion. None of these six women was seriously ill and the res...