نتایج جستجو برای: nitrosamines
تعداد نتایج: 1291 فیلتر نتایج به سال:
BACKGROUND Previous epidemiologic studies found inconsistent results for the association between red meat intake, nitrosamines [NDMA: N-nitrosodimethylamine, and ENOC (endogenous nitroso compounds)], and the risk of bladder cancer. We investigated the association between red meat consumption, dietary nitrosamines, and heme iron and the risk of bladder cancer among participants of the European P...
Relationship of Rat Urinary Metabolites of /V-Nitrosomethyl-A/-alkylamine to Bladder Carcinogenesis1
Nitrosomethylalkylamines with chain lengths from C4 (n-butyl-) to OK (n-tetradecyl-) were each administered to three rats at doses equimolar with 12 mg of the butyl compound. All of the compounds administered to rats at this dose, twice a week for 30 weeks, induced tumors in 100% of the animals. Some of the compounds with even-numbered alkyl chains induced bladder tumors, and a connection was s...
Regarding food borne intoxications, the accumulation of biogenic amines must be avoided in all kinds of food products. Moreover, biogenic amines can function as precursors for the formation of carcinogenic N-nitrosamines when nitrite is present. To estimate the food safety of the dry fermented sausages available on the Belgian market, a screening of the residual sodium nitrite and nitrate conte...
A new method for the simultaneous determination of hemoglobin adducts from aromatic amines and tobacco-specific nitrosamines (TSNA) is described. After mild base-catalysed hydrolysis releasing aromatic amines and the TSNA adduct 4-hydroxy-1-(3-pyridyl)-1butanone (HPB), the extraction, cleanup, and concentration are performed by a one-step procedure using C 1 8 cartridges. Determination in the p...
2. Furthermore, NIPH was asked by Klif to evaluate existing risk estimates for Nnitrosodimethylamine (NDMA). This includes an evaluation of EPA/IRIS risk estimates for drinking water and air, and other risk estimates of this nitrosamine in Europe or Canada. Klif wanted an evaluation of the validity of the values, how they can be used, and how they should be interpreted. NIPH was also asked to c...
A new study in the Journal of Alzheimer's Disease finds a strong link between some food preservatives and an increased risk of death from Alzheimer's, Parkinson's and diabetes. These food additives have previously been linked with several different types of cancer, including prostate, colon and rectum. Sodium and potassium nitrates are used in the processes of salting, pickling and curing foods...
It is now well established that cured meat products such as bacon contain trace amounts of N-nitrosodimethylaminel and that on cooking, N-nitrosopyrrolidine is f ~ r m e d . ~ ~ The origin of the N-nitrosopyrrolidine is not conclusively established, but may be formed from proline by nitrosation and subsequent decarb~xylation.~ The present study is restricted to the determination of these two ni...
This review discusses a new aspect to the safety profile of oxidative hair dyes using data already in the public domain. These dyes contain secondary amines that are capable of forming potentially carcinogenic nitrosamine derivatives when exposed to atmospheric pollution. Numerous scientific articles confirm the existence of secondary amines in hair dyes (and their intermediates), the possibili...
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