Atrial natriuretic peptide (ANP) has natriuretic and vasodilator actions that lower arterial pressure and may be beneficial to hypertensive patients. To assess the effects of ANP on left ventricular function in patients with hypertension, we compared it with the pure vasodilator nitroprusside. Simultaneous left ventricular micromanometer pressure and radionuclide volume were obtained at baselin...

Left ventricular pressure and segment length were measured in seven conscious chronically instrumented dogs with the pericardium intact and 3-9 days after pericardiectomy. Diastolic pressure-length plots were obtained under control conditions and after acute volume loading followed by sodium nitroprusside infusion. In all dogs with intact pericardium, volume loading displaced the entire diastol...

OBJECTIVE Sodium nitroprusside is a direct-acting vasodilator used to lower blood pressure in the operating room and ICU. The efficacy of sodium nitroprusside has been analyzed in few pediatric randomized trials. This study assesses the efficacy and safety of sodium nitroprusside following at least 12 hours of IV infusion in children. DESIGN Randomized, double-blind withdrawal to placebo stud...

to find the protective role of exogenous nitric oxide (no) on salinity-stressed rice seedlings, a crd-based factorial experiment with three replications was conducted in agronomy laboratory of the faculty of agricultural sciences, university of guilan, in 2012. the experimental design consisted of healthy and vigorous seedlings of two rice cultivars, khazar and goohar, the last already known as...

copper is a micronutrient which its, deficiency can alter essential functions in plant metabolism. on the other hand, excess copper is present in certain regions and environments, and can be potentially toxic to plants causing phytotoxicity by the formation of reactive oxygen species that damage cells. in this study, we examined the effect interactions between various concentrations of sodium n...

Abstract: Analyses of germination seeds under artificial stress conditions are tools for a better understanding the survival and adaptation capacity species natural conditions. Therefore, aim this study was to evaluate effect priming on seed germination, breaking dormancy, length Urochloa brizantha seedlings water restriction salt A completely randomized experimental design used with four repli...

The purpose of this study was to investigate the relationship between sodium nitroprusside-induced relaxation, inhibition of the sodium-potassium pump, and cyclic guanosine monophosphate. Exposure of rat thoracic aorta to ouabain, or potassium- or magnesium-free Krebs-Ringer bicarbonate solution, procedures which presumably inhibit the sodium-potassium pump, or to potassium chloride or tetraeth...

In patients with malignant hypertension, immediate blood pressure reduction is indicated to prevent further organ damage. Because cerebral autoregulatory capacity is impaired in these patients, a pharmacologically induced decline of blood pressure reduces cerebral blood flow with the danger of cerebral hypoperfusion. We compared the reduction in transcranial Doppler-determined middle cerebral a...