introduction: different vasoactive factors can modulate cardiovascular adaptation to hemorrhagic shock including nitric oxide (no). in this study we investigated the effect of  the no synthase inhibitor for treatment of  decompensated hemorrhagic shock in normotensive and hypertensive rats. methods: twenty‑four male wistar rats were divided into two groups: the normotensive and hypertensive gro...

background: a number of medicinal plants have been used to treat various immunological diseases. nitric oxide (no) has an important regulatory role in the various types of inflammatory processes. objective: to investigate the no modulatory activity of the extracts of several medicinal plants native to iran including dracocephalum kotschyi, linum persicum, dionysia termeana, salvia mirzayanii, f...

background since nitric oxide (no) has an oxidant activity, lower levels following a varicocelectomy may result in better functioning sperm, improved semen quality and consequently higher fertility rates. however, this procedure should be examined in more detail. objectives accordingly, this study was performed to compare the before and after varicocelectomy levels of no in the seminal fluid of...

Nitric oxide is produced by almost all cardiac cells, endothelial cells, cardiomyocytes and nerve fibers. It is synthesized by an enzyme, a nitric oxide synthase, which occurs in endothelial, neural and inducible form. The distribution of nitric oxide synthase in the heart is characterized by a pronounced non-uniformity. Nitric oxide exerts its effects in physiological and pathophysiological co...

a rapid isocratic method of high performance liquid chromatography system (hplc) with a glassy carbon working electrode of electrochemical detector is set up for quantitative detection of  trace amount of nitrite ion (no2¯) in aqueous protein containing cell lysate, cell media, plasma, serum, urine and other body fluids. the solid extraction  reversed phase cartridges (sep-pak) are used for dep...

objective: nitric oxide (no) plays an important role both as a consequence and as a cause of epileptic seizures.regarding the central nervous system depressant effects of achillea wilhelmsii (a. wilhelmsii), as well the effects of the plant on no, this study was aimed to elucidatethe possible role for nitric oxide on the effects of hydroalcoholic extract of a. wilhelmsii on pentylenetetrazole (...

objective: it has been shown that silybum marianum or its extracts have hepatoprotective, antioxidant, anticancer, anti-inflammatory and anti-diabetic effects. nitric oxide (no) plays an important role in neurotransmission, neuroprotection, neurotoxicity and pathological pain, as a neurotransmitter or neuromodulator in the central nervous system. therefore, this experiment was performed in orde...

the catastrophic effects of opioids use on public health and the economy are documented clearly in numerous studies. repeated morphine administration can lead to either a decrease (tolerance) or an increase (sensitization) in its behavioral and rewarding effects. morphine-induced sensitization is a major problem and plays an important role in abuse of the opioid drugs. studies reported that mor...

clinical studies have shown that in pathological conditions such as endometriosis and reproductive tract infection (male and female) there is an activation status of macrophages that produce large quantities of nitric oxide (no) in addition to other effector molecules. large amounts of no may have embryotoxic roles and produce infertility. this study was designed to evaluate the effect of diffe...

background:   objective: the aim of this study was to evaluate the expression of enos in the fts of women with tep.   materials and methods: in this case-control study, a total number of 30fts samples were obtained from three groups including: 10 fts of women that bearing an ep, 10 fts from the non-pregnant women at luteal phase of the menstrual cycle, and 10 fts of healthy pregnant women (n=10...