Ascorbic acid and nitric oxide are known to play important roles in epilepsy. The aim of present study was to identify the involvement of nitric oxide (NO) in the anticonvulsant effects of ascorbic acid on penicillin-induced epileptiform activity in rats. Intracortical injection of penicillin (500, International Units (IU)) into the left sensorimotor cortex induced epileptiform activity within ...

The effect of L(+)ascorbic acid and/or sodium nitrate in nitric oxide production by hepatocytes in vitro was studied. It was demonstrated that the compounds added into an incubation medium stimulated nitric oxide production in hepatocytes. The highest concentration of nitric oxide was assayed after the incubation of the cells with sodium nitrate and L(+)ascorbic acid. It was found that the addi...

D. Y. Wang, M. Höpfner, G. Mengistu Tsidu, G. P. Stiller, T. von Clarmann, H. Fischer, T. Blumenstock , N. Glatthor, U. Grabowski, F. Hase, S. Kellmann, A. Linden, M. Milz, H. Oelhaf, M. Schneider, T. Steck, G. Wetzel, M. López-Puertas, B. Funke, M. E. Koukouli, H. Nakajima, T. Sugita, H. Irie, J. Urban, D. Murtagh, M. L. Santee, G. Toon, M. R. Gunson, F. W. Irion, C. D. Boone, K. Walker, and P...

The alteration of two trioctahedral micas, biotite and phlogopite, was investigated at the meso, micro, nanoscale using three complementary microscopy techniques to better understand mica surface reactivity. In situ ex experiments were performed monitor mineral interface during dissolution in acidic solutions (nitric oxalic acid, pH ∼ 1–2), over a temperature range 25–100°C. inorganic acid used...