The possibility to reprogram somatic human cells will greatly and deeply change genetic approach and allow the development of new tools to study genetics diseases. Indeed, our ability to study human genetic diseases suffers from the lack of valid in vitro models. The latter should (i) be originating from human primary cells, (ii) be able to self-renew for a long time and (iii) be able to differ...

The aim of this study was to identify the cell surface cluster of differentiation (CD) markers of the cell lines infected by Theileria annulata schizont. The CD molecules are very useful for the characterization of cells and different subpopulations of leukocytes. They are usually recognized by specific antibodies using flow cytometry and immunohistochemistry. In the current stud...

Objective(s):Berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. But the effect of berberine on breast cancer has not yet been completely studied. In this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. Materials and Methods: The antiproliferative effects of berberine and doxorubicin alone and in ...

Imagine turning out a 1.5 million-line Ada command and control system for a Navy frigate warship. The system is hard real-time, faulttolerant, and highly distributed, running on 70 separate processors on 30 different local area network nodes scattered all over the ship. It must interface with radars and other sensors, missile and torpedo launchers, and other complicated devices. The human-compu...

Mating of Ascomycete fungi involves chemically distinct pheromones; one partner makes a lipid-modified peptide, the other partner a simple peptide. A new study has now found that this inherent asymmetry may not be necessary.

the new cereal, primary tritipyrum lines, is an artificial hexaploeid wheat (2n=6x=42, aabbebeb) from crossing between triticum durum (2n=4x=28, aabb) and thinopyrum bessarabicum (2n=2x=14, ebeb) species. in this study the salt tolerant potencial of new primary tritipyrum lines for nacl (0, 100, 200 mm) in an hydroponic experiment was studied in a completely randomized split plot design with th...

An SPICE compatible model for multiple coupled nonuniform lossless transmission lines (TL's) is presented. The method of the modeling is based on the steplines approximation of the nonuniform TLs and quasi-TEM assumptions. Using steplines approximation the system of coupled nonuniform TLs is subdivided into arbitrary large number of coupled uniform lines (steplines) with different characteristi...

We have characterized two new transgenic Xenopus lines enabling transgene expression using the Tet-On inducible system. An inducer line expresses the doxycycline- (Dox-) activated transcription factor rtTA under control of the ubiquitous promoter CMV. A responder line enables Dox-inducible expression of a dominant positive thyroid hormone receptor via a tetracycline responsive transgenic promot...