Selective routing of information between cortical areas is required in order to combine different sources of information according to cognitive demand. Recent experiments have suggested that alpha band activity originating from the pulvinar coordinates this inter-areal cortical communication. Using a computer model we investigated whether top-down induced shifts in the relative alpha phase betw...

BACKGROUND Gap junction communication has been shown in glial and neuronal cells and it is thought they mediate inter- and intra-cellular communication. Connexin 36 (Cx36) is expressed extensively in the developing brain, with levels peaking at P14 after which its levels fall and its expression becomes entirely neuronal. These and other data have led to the hypothesis that Cx36 may direct neuro...

one of the most important problems in neuroscience researches is the understanding what is the communication between the immune system and central nervous system. proinflammatory factors play an important role in this communication. the dysregulation of proinflammatory factors such as cytokines and chemokines is a central feature in the development of neuroinflammation.one of the important  cyt...

Selective attention relies on dynamic restructuring of cortical information flow in order to prioritize neuronal communication between those neuronal groups conveying information about behaviorally relevant information, while reducing the influence from groups encoding irrelevant and distracting information. Electrophysiological evidence suggests that such selective neuronal communication is in...

Neuronal processes (neurites and axons) have an important role in brain cells communication and, generally, they are damaged in neurodegenerative diseases. Recent evidence has showed that the activation of PPARγ pathway promoted neuronal differentiation and axon polarity. In addition, activation of PPARγ using thiazolidinediones (TZDs) prevented neurodegeneration by reducing neuronal death, imp...

Abstract Norepinephrine (NE) is a ubiquitous neurotransmitter that facilitates cellular communication in the sympathetic nervous system. Recent advancements have shown neurons innervate secondary immune organs, such as spleen, to control physiology. Fast-scan cyclic voltammetry (FSCV) an electrochemical technique varies applied potential at very fast scan rate with micro-electrodes detect neuro...

A typical feature of astrocytes is their high degree of intercellular communication through gap junction channels. Using different models of astrocyte cultures and astrocyte/neuron cocultures, we have demonstrated that neurons upregulate gap-junctional communication and the expression of connexin 43 (Cx43) in astrocytes. The propagation of intercellular calcium waves triggered in astrocytes by ...