Dihydroxyphenylalanine decarboxylase and 5-hydroxytryptophan decarboxylase respectively have high and low affinities for pyridoxal phosphate. In the pyridoxine-deficient animal, hypothalamic serotonin content is significantly reduced without any change in catecholamine levels. Hypothalamic neurotransmitters affect the hypothalamo-pituitary-end organ axes. Specifically, the decrease in hypothala...

Neuroendocrinology is the field of research that explores the interplay between the central nervous system and the endocrine glands. The neuroendocrine system controls a number of essential physiological processes, including biological rhythms, stress, social behaviors, appetite, growth, and reproduction. The present Research Topic is a compilation of contributions stemming from the 8th Interna...

A large body of evidence indicates that individual differences in baseline concentrations of testosterone (T) are only weakly correlated with human aggression. Importantly, T concentrations are not static, but rather fluctuate rapidly in the context of competitive interactions, suggesting that acute fluctuations in T may be more relevant for our understanding of the neuroendocrine mechanisms un...