نتایج جستجو برای: neural stem

تعداد نتایج: 561654  

Introduction: The features of a cell can be extracted from its gene expression profile. If the gene expression profiles of future descendant cells are predicted, the features of the future cells are also predicted. The objective of this study was to design an artificial neural network to predict gene expression profiles of descendant cells that will be generated by division/differentiation of h...

Objective: Arsenic, an environmental pollutant, decreases neuronal migration as well as cellular maturation and inhibits the proliferation of neural progenitor cells. Curcumin has been described as an antioxidant and neuroprotective agent with strong therapeutic potential in some neurological disorders. Human adipose-derived stem cells (hADSCs), a source of multipotent stem cells, can self-rene...

Hossein Baharvand, Khadije Karbalaei, Maryam Anjomshoaa, Mohammad Hossien Nasr Esfahani, Mohammad Mardani, Shahnaz Razavi, Somayeh Tanhaei,

Introduction: The aim of this study was evaluate the ability of notochord to induce neural induction and/or differentiation of mouse embryonic stem cell to neuron and motor neuron, respectively. Methods: In order to produce embryoid bodies, ES cells line Royan B1 were grown in suspension in the absence of LIF for 4 days. EBs were divided into 4 groups. EBs in group 1 & 2 were further cultur...

Objective(s): In the past few decades, variety of foetal, embryonic and adult stem and progenitor cells have been tried with conflicting outcome for cell therapy of central nervous system injury and diseases. Cellular characteristics and functional plasticity of Globose basal stem cells (GBCs) residing in the olfactory epithelium of rat olfactory mucosa have not been studied in the past by the ...

Journal: :مجله علوم اعصاب شفای خاتم 0
yasaman behmanesh islamic azad university, mashhad branch, mashhad, iran nafise bahrami islamic azad university, mashhad branch, mashhad, iran zahra ghane islamic azad university, mashhad branch, mashhad, iran

adult neurogenesis is a process of producing nerve cells from their progenitor that occurs in some areas in the brain such as the hypothalamus. low activity in this area plays a role in neural degeneration and diseases such as multiple sclerosis, epilepsy and depression. ms is a neurodegenerative disease with a permanent disability that the main reason for it is axonal degeneration and neuronal...

Journal: :مجله علوم اعصاب شفای خاتم 0
prastoo barati shefa neuroscience research center, khatam alanbia hospital, tehran, iran. taghi tiraihi a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran. b. department of anatomy, tarbiat modares university, tehran, iran. marzieh darvishi a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran. b. department of anatomy, tarbiat modares university, tehran, iran. hadi kazemi shefa neuroscience research center, khatam alanbia hospital, tehran, iran.

in the last few years, a lot of preclinical studies showed the therapeutic potential of stem cells in spinal cord injury (sci). neural stem cells (nscs) can be differentiated into all cell types of spinal cord. nscs are cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair of injury in central nervous system. here in, we describe the ef...

Nasibeh Ghandy, Sajad Sahab Negah,

Traumatic brain injury (TBI) is defined as an external mechanical injury to the brain. Neuroinflammation plays a vital role in the pathophysiology of TBI. Microglia and astrocytes play a central role in the initiation and regulation of inflammation. Numerous pro-inflammatory mediators including cytokines, chemokines, reactive oxygen species (ROS) and nitric oxide (NO) released by microglia. In ...

Objective(s): Cell therapy has provided clinical applications to the treatment of motor neuron diseases. The current obstacle in stem cell therapy is to direct differentiation of stem cells into neurons in the neurodegenerative disorders. Biomaterial scaffolds can improve cell differentiation and are widely used in translational medicine and tissue engineering. The aim...

Journal: :مجله علوم اعصاب شفای خاتم 0
hadi aligholi a. department of neuroscience, school of advanced medical sciences and technologies, shiraz university of medical sciences, shiraz, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iran mohammad torabi-nami department of neuroscience, school of advanced medical sciences and technologies, shiraz university of medical sciences, shiraz, iran bijan zare department of medical biotechnology, school of advanced medical sciences and technologies, shiraz university of medical sciences, shiraz, iran

spinal cord injury (sci) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. to date, there is no definite treatment for repairing damaged spinal cord tissue. in this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, schwann cells,...

Bijan Zare, Hadi Aligholi, Mohammad Torabi-Nami,

Spinal cord injury (SCI) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. To date, there is no definite treatment for repairing damaged spinal cord tissue. In this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, Schwann cells,...

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