spinal cord injury (sci) results in the damage of motor and sensory pathways. the molecular and cellular structure of the injury milieu has been shown to be vital for endogenous regeneration in most tissues. regeneration of injured central nervous system (cns) is limited by damaged cell environment. biomaterial scaffolds can reconstruct injured cns tissue following sci by promoting the migratio...

To study the neuropathic pain mechanism, various behavioral responses of animals in to different neuropathic models were considered. Adult male Sprague-Dawley rats weighing 230-280 g were used. Anesthesia was initially induced with pentobarbital I.P. (50 mg/kg). These models included (1): chronic constriction injury (CCI) by loose ligation of the sciatic nerve (2) Spared nerve injury (SNI) by a...

introduction: ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. as dexamethasone (dex) has been shown to prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. methods: 36 male wistar rats (200-250 gr) were chosen and divided randomly into 6 equal groups...

Temporary or permanent vocal cord paralysis caused by recurrent laryngeal nerve injury is one of the relatively common and serious complications thyroid surgery. At same time, there are many reasons for injury. Therefore, should be paid attention to before, during after A 51-year-old woman was diagnosed with left papillary carcinoma. Unfortunately, patient had a history hoarseness following pat...

Introduction: Transplantation of bone marrow stromal cells (BMSCs) or Schwann cells (SCs) can increase axonal regeneration in peripheral nerve injuries. Based on our previous investigations, the goal of the present work was to examine the individual and synergistic effects of the two different cell types in sciatic nerve injury . We pursued to evaluate the effects of BMSCs and SCs co-transplant...

introduction: malignant tumors of the parotid gland account scarcely for 5% of all head and neck tumors. most of these neoplasms have a high tendency for recurrence, local infiltration, perineural extension, and metastasis. although uncommon, these malignant tumors require complex surgical treatment sometimes involving a total parotidectomy including a complete facial nerve resection. severe fu...

Wallerian degeneration is an innate immune response which occurs after some kinds of nerve damages such as neurodegenerative disease and acute axonal injury. In clinic, dexamethasone as an anti-inflammatory drug has been used for many years to treat nerve injuries. In present study, we aimed to study the effects of various doses of dexamethasone on the Wallerian degeneration in rat. Twentyseven ...