The morphology and distribution of the cholinergic and adrenergic nerve fibres were described in the thyroid gland of the domestic hen. The adrenergic structures were visualised with glyoxylic acid and with immunohistochemical staining for tyrosine hydroxylase (TH), the marker for adrenergic nerve structures. Cholinergic structures were visualised using the Karnovsky and Roots method. It was fo...

WE-14 is generated in subpopulations of chromogranin A immunopositive endocrine cells and neurons including those innervating the anterior uvea. This study investigated WE-14 in intact sclero-limbo-corneal tissue from embryonic (E17), neonatal (N0-N16), and adult mice using immunocytochemistry and confocal scanning laser microscopy. Weak WE-14 immunostaining was observed at birth in nerve fibre...

Multiple endocrine neoplasia 2B (MEN2B) is a rare syndrome caused by an activating mutation of the RET gene, leading to enteric gangliomatosis. This child presented with constipation at 1-mo old, was diagnosed with MEN2B by rectal biopsy at 4 mo, had thyroidectomy at 9 mo and a colectomy at 4 years. We studied the extent of neuronal and nerve fibre proliferation and which classes of enteric ner...

Median nerve sensory fibres were stimulated with minimal and supramaximal stimuli at the base of the third digit in 30 normal subjects. Evoked nerve action potentials were simultaneously recorded from two points on the median nerve just above the wrist. As stimulus voltage was increased from minimal to supramaximal, amplitudes of nerve action potentials increased, latencies decreased, but condu...

The tracheal and bronchial parasympathetic ganglia in the cat were studied using the histochemical-tiocholine method of Koelle and Friedenwald and histological techniques. Intensively stained AChE-positive nerve structures, i.e., ganglia and nerve fibres on the wall of the trachea and bronchi, were observed. The ganglia were situated mainly on the dorso-lateral surface of these organs, but they...

BACKGROUND The cholinergic neurotransmission within the human mesenteric lymphatic vessels has been poorly studied. Therefore, our aim is to analyse the cholinergic nerve fibres of lymphatic vessels using the traditional enzymatic techniques of staining, plus the biochemical modifications of acetylcholinesterase (AChE) activity. MATERIALS AND METHODS Specimens obtained from human mesenteric l...

The distribution of galanin-containing nervous elements in the chicken pancreas was investigated by use of immunohistochemical method. Galanin-immunoreactive nerve fibres formed a perivascular plexus and a dense network in the subepithelial layer of secretory ducts. The muscle layers of secretory ducts were also supplied with galanin-immunoreactive nerve fibres. The exocrine pancreas received a...

The physiological phenomenon of mydriasis may be produced by the action of a number of alkaloidal bodies, and is known to bear a certain relationship to their chemical structure. A dilatation of the pupil may theoretically be produced by a paralysis of the circular muscle fibres of the iris, or of the endings of the oculo-motor nerve, or by the stimulation of the radial muscle fibres, or of the...

Peripheral nerves in five patients with rheumatoid neuropathy were examined electrophysiologically and by sural nerve biopsy. There was close correlation between the clinical severity of the disease and the degree of nerve damage found histologically and by EMG. Group 1 patients with a mild distal sensory neuropathy showed varying degrees of axonal degeneration in the large myelinated fibres an...

The distribution of somatostatin-immunoreactive nerve fibres in Peyer's patches of the cat was demonstrated by immunocytochemical techniques. A large number of immunoreactive nerve fibres was observed in the tela submucosa very close to the Peyer's patches. Some immunoreactive nerve cell bodies were also found in this layer. The immunoreactive nerve terminals ran around the margin of the follic...