objective(s):diabetic neuropathy (dn) is a common complication of diabetes that leads to allodynia, impaired nerve conduction, and progressive sensory loss. the aim of this study was to observe the effect of a high-affinity cannabinoid receptors agonist, win 55,212-2, on thermal hyperalgesia, nerve conduction velocity and sciatic nerve histopathology in diabetic rats. materials and methods: dia...

In the short-fibered non-striated probascis retractor of phascolosoma (Golfingia gouldii) , 3 conduction is entirely by intrinsic nerve fibers. Evidence for nerve conduction is: velocity of propagation (1.3 and 0.3 m/second for fast and slow responses, respectively), abundance of nerve fibers, block by nerve-blocking drugs, failure of propagation after nerve degeneration, and detection of nerve...

Aim: Inferior dental anaesthesia via the direct intraoral approach, mandibular conduction anaesthesia via extraoral landmarks (Gow-Gates) and mandibular conduction anaesthesia via the tuberosity approach (Akinosi) were evaluated using pain during injection, aspiration test, pinprick, depth and frequency of anaesthesia, onset and duration of anaesthesia. Materials and Methods: 120 patients of bo...

The isolated rat phrenic nerve/diaphragm preparation has proven to be a useful tool for examining neuromuscular transmission and function in vitro. This preparation allows for the simultaneous examination of direct phrenic nerve stimulation as well as direct muscle stimulation. While the isolated phrenic nerve/diaphragm has been extensively utilized (Bulbring, 1946; Tsai, 1985; Wali et al., 198...

Studies in experimental diabetic rat attribute the acute reversible nerve conduction defect as well as the early structural abnormalities of the node of Ranvier and myelinated axons to changes in nerve metabolism secondary to hyperglycaemia and activation of the pol yo1 pathway.’-8 The early readily reversible slowing of nerve conduction velocity in the diabetic rats correlates with a decrease ...

The spatio-temporal expression patterns of mRNA transcripts coding for acetylcholine receptor (AChR) subunits and myogenic factors were measured in denervated rat soleus muscle and in soleus muscle chronically paralyzed for up to 12 d by conduction block of the sciatic nerve by tetrodotoxin (TTX). In denervated muscle the AChR alpha-, beta-, gamma-, and delta-subunit mRNAs were elevated with hi...

Objective: We studied sequential waveform changes associated with a progressive conduction block to elucidate the relative vulnerability of slow versus fast conducting ®bers to a focal compression. Methods: In 12 healthy men, orthodromic compound sensory nerve action potentials (SNAPs) of the median nerve were recorded unipolarly at 4 sites over the forearm during a 30 min period of constant, l...

Inferior dental anaesthesia via the direct intraoral approach, mandibular conduction anaesthesia via extraoral landmarks(Gow-Gates) and mandibular conduction anaesthesia via the tuberosity approach( Akinosi) were evaluated using pain during injection, aspiration test, pinprick, depth and frequency of anaesthesia, onset and duration of anaesthesia. 120 patients of both sexes, aged from 16 years ...