نتایج جستجو برای: nep1
تعداد نتایج: 74 فیلتر نتایج به سال:
niaid.nih.gov Identification of evolutionarily conserved segments of homology within DNA regulatory regions, ‘phylogenetic footprints’, provides a means for discovering functionally relevant site-specific DNAbinding proteins. This approach has its drawbacks, however, because it depends on the conservation of sequences in pivotal cis regulatory elements. In some instances, functionally analogous...
Stroke is the leading cause of disability in much of the world, with few treatment options available. Following unilateral stroke in rats, inosine, a naturally occurring purine nucleoside, stimulates the growth of projections from the undamaged hemisphere into denervated areas of the spinal cord and improves skilled use of the impaired forelimb. Inosine augments neurons' intrinsic growth potent...
The proteins in DUF358 family are all bacterial proteins, which are ∼200 amino acids long with unknown function. Bioinformatics analysis suggests that these proteins contain several conserved arginines and aspartates that might adopt SPOUT-class fold. Here we report crystal structure of Methanocaldococcus jannaschii DUF358/Mj1640 in complex with S-adenosyl-L-methionine (SAM) at 1.4 Å resolution...
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