Solid-pseudopapillary neoplasm (SPN) of the pancreas is a rare neoplasm reported to have a favourable prognosis because of its slow-growing behaviour. Ignored and misdiagnosed in the past, SPN has recently been increasingly studied. Its clear cell variant creates challenges in distinction from other clear cell tumours in the pancreas. We report a 31-year-old Cambodian woman who presented with a...

Tongue squamous cell carcinoma (TSCC) is an aggressive neoplasm which typically spreads through invasive growth with serious morbidity and mortality. Previous studies suggested that the expression of LRIG1 functions as the vital suppressor gene in various human cancer types by inhibiting invasion and proliferation. However, little is known about the downstream genes coordinating this process in...

BACKGROUND It is often difficult to diagnose salivary gland tumors that exhibit basaloid features differentially. The aim of this study was to identify additional morphological and immunohistochemical characteristics that can aid the diagnosis of basal cell adenocarcinoma (BCAC) of the salivary gland. METHODS AND RESULTS In total, 29 basal cell neoplasms [eight BCACs, 11 basal cell adenomas (...

Thyroid cancer is one of the most prevalent endocrine neoplasm. The present study examined the effects of Colorectal Neoplasia Differentially Expressed (CRNDE) on the progression of papillary thyroid cancer (PTC), and explored the underlying molecular mechanisms. Quantitative real-time PCR was used to detect CRNDE, miR-384 and pleiotrophin (PTN) mRNA expression. Western blot was used to measure...

MicroRNAs (miRs) play important roles in modulating gene expression during the processes of tumorigenesis and tumor development. Previous studies have found that miR-145 is down-regulated in the stomach neoplasm and is related to tumor migration and invasion. However, both the molecular mechanism and function of miR-145 in gastric cancer remain unclear. The present study is the first demonstrat...

a set of one hundred and twenty nine patients with known primary malignancy and suspected brain metastasis was reviewed in present study. the patients were selected among patients presented to the mri section of imam khomeini hospital or a private mri center in tabriz (iran). primary tumor site, clinical manifestations, number and site of lesions were identified in this patient population. the ...

Primary intracranial myxofibrosarcoma is exceedingly rare, with less than 10 cases published. We present a case of a 23-year-old man with previous history of a primary low grade myxofibrosarcoma of the left parietal-occipital convexity resected in March 1999. He subsequently underwent several interventions for multiple local recurrent disease until March 2004. At that time, complete remission w...

Thymic malignancy is rare in horses. Thymic epithelial tumor was diagnosed in an 18-year-old mare with invasion and metastasis to the pericardium and heart. At necropsy, the cranial thoracic cavity was obliterated by a large mass located in the thymic region and the right atrium was also expanded and effaced by a similar mass. Histologically, the neoplasm was composed of sheets of spindle cells...

A thirty six-year old woman was treated for acute massive upper gastrointestinal bleeding in a local hospital. A day after the bleeding she was referred to the 5th City Hospital of Moscow. Due to severe anemia and jaundice the patient was admitted to the intensive care unit and after computed tomography and endoscopy a multi-nodular tumor of the pancreatic head, body and tail with invasion of t...

abstract background: abdominal tumors are still a diagnostic problem in children. this study was conducted to assess the presentation and types of childhood intra abdominal tumors in children in shiraz. materials and methods: participants of this historical cohort study consisted of 298 children aged between 1.5 months to 15 years old who were diagnosed with abdominal mass between march 2003 an...