On Neonatal Intensive Care Units (NICU) many vital parameters are recorded but monitoring of brain function by Electroencephalography (EEG) is rare, mainly because signal interpretation requires expert visual inspection. In 1-6 % of newborns on the NICU (sub clinical) seizures occur and even more frequent in prematures and lowbirth weight children [1]. Failure of detection and subsequent lack o...

OBJECTIVES The objectives of this study were to delineate the etiologic profile and neurodevelopmental outcome of neonatal seizures in the current era of neonatal intensive care and to identify predictors of neurodevelopmental outcome in survivors. METHODS Eighty-nine term infants with clinical neonatal seizures underwent neurologic examination, electroencephalography (EEG), neuroimaging, and...

OBJECTIVE To determine the interobserver agreement (IOA) of neonatal seizure detection using the gold standard of conventional, multichannel EEG. METHODS A cohort of full-term neonates at risk of acute encephalopathy was included in this prospective study. The EEG recordings of these neonates were independently reviewed for seizures by three international experts. The IOA was estimated using ...

OBJECTIVE Prevalence of neonatal stroke has been reported 1/2300-1/4000 live births and accounts for 12-20% of the cases of neonatal seizures. Although stroke has been introduced as the second cause of the neonatal seizures in literatures, it may remain unclear in diagnostic evaluations of seizure in neonates. This study was performed to assess the prevalence of stroke in neonates with seizure....

relatively expensive, are generally used for only a few hours of monitoring, and may not be routinely available in many centers. Automated processing and analysis of video recordings of neonatal seizures can generate novel methods for extracting quantitative information that is relevant only to the seizure. The extraction of quantitative information from video recordings of neonatal seizures ca...

A seizure is defined clinically as paroxysmal alternations in neurological function, namely, motor, behavioral, or autonomic function. Neonatal seizures tend to be brief, because immature neurons cannot sustain repetitive activity for a long time and tend to be focal or multifocal. Neonatal seizures are common: estimates of the incidence of clinical seizures in term infants range from 0.7-2.7 p...