PURPOSE Since 1997, private postnatal care facilities (San-hu-jo-ri-won in Korean) have emerged to take the role of the family. As a result, neonates are now exposed to many people and are very vulnerable to infection. However, there has been no study on the influence of postnatal care facilities on neonatal infection. The aim of this study was to determine the risk factors of neonatal infectio...

During the last two decades, dramatic improvement in survival of newborns, especially the extremely premature group, resulted from major advances such as antenatal steroids and surfactant, as well as from many other less dramatic improvements in care. As fewer babies died of respiratory failure and smaller babies survive, infection has become an increasingly important cause of mortality and mor...

Background: Introduction: Searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. There are many biomarkers reported for neonatal sepsis. Haptoglobin is an acute phase reactants which rise in response to infection and injuries. In this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

Tremendous advances have occurred over the past 30 years in the diagnosis and management of neonatal herpes simplex virus (HSV) disease. Mortality in patients with disseminated disease has decreased from 85 to 29%, and that in patients with central nervous system (CNS) disease has decreased from 50 to 4%. Morbidity has been improved more modestly: the proportion of patients with disseminated di...

Chikungunya virus is a member of the genus Alphavirus, in the family Togaviridae. Infected mosquitoes can spread the virus to other humans when they bite. The symptoms include fever, petechial or maculopapular rash and arthralgia or arthritis affecting multiple joints mainly in adults. The illness is usually self-limiting and will resolve with time. The time of greatest risk of transmission fro...

OBJECTIVE To determine if amnioinfusion with an antibiotic solution decreased the rate of clinical chorioamnionitis and puerperal endometritis in patients with meconium-stained amniotic fluid. METHODS Patients in labor at 36 weeks of gestation or greater with singleton pregnancies and meconium-stained amniotic fluid were randomized to receive either cefazolin, 1 g/1,000 mL, of normal saline (...

The objective of this study was to determine whether Lactobacillus rhamnosus GG culture supernatant (LCS) has a preventive effect against gut-derived systemic neonatal Escherichia coli (E. coli) K1 infection. The preventive effects were evaluated in human colonic carcinoma cell line Caco-2 and neonatal rat models. Our in vitro results showed that LCS could block adhesion, invasion and transloca...