fibrodysplasia ossificans progressiva (fop) is a rare hereditary connective tissue disease characterized by the progressive ectopic ossification of ligaments, tendons, and facial and skeletal muscles throughout life. symptoms begin in childhood as localized soft tissue swellings. immobility and articular dysfunction appear with involvement of the spine and proximal extremities. the temporomandi...

A 31-year-old female hairdresser whose parents were first degree cousins complained of episodic attacks headache, vomiting, and dizziness for the past eight years after an uneventful childhood adolescence. Four ago, she developed progressive weakness, muscle pain difficulties walking lifting her arms that could not work in profession anymore. She lost hair, weight became amenorrhoic. Finally, w...

In this case, we describe an unusual presentation of a young woman with a rash typical of morphoea (confirmed on biopsy), who went on to develop myositis in an atypical distribution. Although the association of myositis with diffuse systemic sclerosis is well described, the link with localised scleroderma (morphoea) and myositis has not been described.

A 69 year old woman with inclusion body myositis is described. She presented with benign monoclonal gammopathy. She was resistant to steroid therapy, but responded to repeated immunoabsorption. Up to now, there has been no established therapy for inclusion body myositis, including IVIg. It is suggested that immunoabsorption could be an alternative therapy for inclusion body myositis, when it wa...

BACKGROUND Interstitial lung disease (ILD) is a prognostic indicator of poor outcome in myositis. Although the pathogenesis of myositis-associated ILD is not well understood, neutrophils are thought to play a pivotal role. Neutrophils store azurophil granules that contain defensins, which are antimicrobial peptides that regulate the inflammatory response. Here, we evaluated levels of the human ...

OBJECTIVES To assess the association between inflammatory lung disease and the risk of developing idiopathic inflammatory myopathies. METHODS A population-based case-control study was conducted. Adult myositis cases, identified from the Swedish inpatient registry (diagnosed between 1995 and 1997), and randomly selected controls matched to cases on the date of birth, gender and residency, were...

Myositis ossificans is a benign self limiting condition that usually related to trauma. Despite a clinically and histologically distinct entity, myositis ossificans still causes considerable difficulties in diagnosis. A 33-year-old Moroccan woman presented with a 2-month history of left inguinal inflammatory pain with limping gait, MRI examination suggested a malignant neoplasm such as soft tis...

Proliferative myositis is a rare pseudosarcomatous inflammatory process. Radiological diagnosis of self-limiting proliferative myositis helps direct appropriate clinical management and avoiding unnecessary surgical excision. We present the ultrasonography, computed tomography, and magnetic resonance imaging findings in a case of proliferative myositis. In this case, malignancy was suspected, an...

Inclusion body myositis is the most common acquired muscle disease in older individuals, and its prevalence varies among countries and ethnic groups. The aetiology and pathogenesis of sporadic inclusion body myositis are still poorly understood; however genetic factors, ageing, and environmental triggers might all have a role. Unlike other inflammatory myopathies, sporadic inclusion body myosit...

INTRODUCTION Myositis ossificans usually occurs in the vicinity of the elbow, knee joints, or hip joints, following obvious trauma or surgery. This is the first report on myositis ossificans of the serratus anterior. CASE PRESENTATION In this report we present a case of myositis ossificans within the serratus anterior which developed as a complication due to long-term nape massage. The patien...