iii DISCLAIMER The contents of this report reflect the views of the authors who are responsible for the facts and accuracy of the data presented herein. The contents do not necessarily reflect the official views or policies of the National Center for Asphalt Technology or Auburn University. This report does not constitute a standard, specification, or regulation. DISCLAIMER All laboratory data,...

OBJECTIVES To investigate the impact of respiratory motion on localization, and quantification of lung lesions for the Gross Tumor Volume utilizing a fully automated Auto3Dreg program and dynamic NURBS-based cardiac-torso digitized phantom (NCAT). METHODS Respiratory motion may result in more than 30% underestimation of the SUV values of lung, liver and kidney tumor lesions. The motion correc...

Introduction Clinical assessment of medical students in emergency medicine (EM) clerkships is a highly variable process that presents unique challenges and opportunities. Currently, clerkship directors use institution-specific tools with unproven validity and reliability that may or may not address competencies valued most highly in the EM setting. Standardization of assessment practices and de...

Introduction: In radiation therapy of lung tumors, respiratory motion causes target moving, so a larger margin is needed to cover the clinical target volume (CTV). With the margin increasing, a larger volume of normal tissue will be exposed to high-dose.  In this study, dosimetric parameters of normal lung tissue were compared between gated and conventional radiotherapy (RT), u...

i DISCLAIMER The contents of this report reflect the views of the authors who are solely responsible for the facts and the accuracy of the data presented herein. The contents do not necessarily reflect the official views and policies of the National Center for Asphalt Technology of Auburn University. This report does not constitute a standard, specification, or regulation.

In PET/CT thoracic imaging, respiratory motion reduces image quality. A solution consists in performing respiratory gated PET acquisitions. The aim of this study was to generate clinically realistic Monte-Carlo respiratory PET data, obtained using the 4D-NCAT numerical phantom and the GATE simulation tool, to assess the impact of respiratory motion and respiratory-motion compensation in PET on ...

Quantitative SPECT as well as simultaneous acquisition of multiple isotopes with SPECT in the clinical field, although clinically interesting, are still limited by reconstruction artifacts and computing power. As a considerable step in this direction, we have implemented an efficient reconstructor with variance reduced Monte-Carlo-simulation in the forward and/or backward projection of an OS-EM...

Purpose: To develop and validate an automatic algorithm for the detection and functional assessment of lung tumors on three-dimensional respiratory gated PET/CT images. Method and Materials: First the algorithm will automatically segment lung regions in CT images, then identify and localize focal increases of activity in lung regions of PET images at each gated bin. Once the tumor voxels have b...

BACKGROUND New algorithms were evaluated for their efficacy in detecting and quantifying serial changes in myocardial perfusion from single photon emission computed tomography (SPECT). METHODS AND RESULTS We generated 72 simulations with various left ventricular positions, sizes, count rates, and perfusion defect severities using the nonuniform rational B-splines (NURBs)-based CArdiac Torso (...