نتایج جستجو برای: nb1 zr

تعداد نتایج: 9811  

2014
Melissa A. Deri Shashikanth Ponnala Brian M. Zeglis Gabor Pohl J. J. Dannenberg Jason S. Lewis Lynn C. Francesconi

Zirconium-89 is an effective radionuclide for antibody-based positron emission tomography (PET) imaging because its physical half-life (78.41 h) matches the biological half-life of IgG antibodies. Desferrioxamine (DFO) is currently the preferred chelator for (89)Zr(4+); however, accumulation of (89)Zr in the bones of mice suggests that (89)Zr(4+) is released from DFO in vivo. An improved chelat...

1970
M. BURNETT G.

representation of the dimeric units of K2[Zr(SO4)3]. 2H20. Examination of this structure shows that breaking and remaking one oxygen bridge in each dimeric ring of K2[Zr(SO4)3.2H20 would result in the formation of infinite-Zr-O-SO -Zr-chains similar to those found in Na2[Zr(SO4)3]. 3H20 [Fig. 3(c)] and we see that in these two compounds we have an extension of the structural arrangements alread...

Journal: :Neuro endocrinology letters 2005
Marek Pawlikowski

It is well known that plasma levels of dehydroepiandrosterone (DHEA), a steroid hormone secreted by zona reticularis (ZR) of the adrenal cortex, reach the maximal values in the third decade of life and then gradually decline with age. Moreover, the DHEA deficiency is probably responsible for several functional disturbances connected with aging. It was also found that ZR reaches its definitive v...

2017
Dongdong Zhang Fang Bai Yong Wang Jinguo Wang Wenquan Wang

The TiCp/Cu master alloy was prepared via thermal explosion reaction. Afterwards, the nano-sized TiCp/Cu master alloy was dispersed by electromagnetic stirring casting into the melting Cu-Cr-Zr alloys to fabricate the nano-sized TiCp-reinforced Cu-Cr-Zr composites. Results show that nano-sized TiCp can effectively refine the grain size of Cu-Cr-Zr alloys. The morphologies of grain in Cu-Cr-Zr c...

2015
Chuangyan Zhai Dominik Summer Christine Rangger Gerben M. Franssen Peter Laverman Hubertus Haas Milos Petrik Roland Haubner Clemens Decristoforo

Within the last years (89)Zr has attracted considerable attention as long-lived radionuclide for positron emission tomography (PET) applications. So far desferrioxamine B (DFO) has been mainly used as bifunctional chelating system. Fusarinine C (FSC), having complexing properties comparable to DFO, was expected to be an alternative with potentially higher stability due to its cyclic structure. ...

2017
Xiaoting Wang Ying Chen Yajun Zheng Zhiping Zhang

The dynamic pore systems and high surface areas of flexible metal-organic framework materials make them excellent candidates to be used in different kinds of adsorption processes. However, the adsorption and desorption behaviors of therapeutic drugs on metal-organic frameworks in solution are not fully developed. Here, we systematically investigated the adsorption and desorption behaviors of a ...

Journal: :Journal of the American Chemical Society 2003
Sebastien Pillet Guang Wu Vichien Kulsomphob Benjamin G Harvey Richard D Ernst Philip Coppens

The crystal structure and electron density (ED) distribution of an imine coupling product with an open zirconocene, Zr(2,4-C(7)H(11))[(i-Pr)NCHPhCH(2)CMe=CHCMe=CH(2)] (C(7)H(11) = dimethylpentadienyl), have been derived from accurate synchrotron X-ray diffraction measurements. The molecular structure reveals asymmetric coordination of Zr by the pentadienyl (2,4-C(7)H(11)) ligand ( = 2.56(...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Neeta Pandit-Taskar Joseph A O'Donoghue Jeremy C Durack Serge K Lyashchenko Sarah M Cheal Volkan Beylergil Robert A Lefkowitz Jorge A Carrasquillo Danny F Martinez Alex Mak Fung Stephen B Solomon Mithat Gönen Glenn Heller Massimo Loda David M Nanus Scott T Tagawa Jarett L Feldman Joseph R Osborne Jason S Lewis Victor E Reuter Wolfgang A Weber Neil H Bander Howard I Scher Steven M Larson Michael J Morris

PURPOSE Standard imaging for assessing osseous metastases in advanced prostate cancer remains focused on altered bone metabolism and is inadequate for diagnostic, prognostic, or predictive purposes. We performed a first-in-human phase I/II study of (89)Zr-DFO-huJ591 ((89)Zr-J591) PET/CT immunoscintigraphy to assess performance characteristics for detecting metastases compared with conventional ...

Journal: :Journal of the National Cancer Institute 2001
L Y Fong V T Nguyen J L Farber

BACKGROUND Nutritional zinc deficiency in rats increases esophageal cell proliferation and the incidence of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumors. Replenishing zinc with a zinc-sufficient diet reduces these effects in zinc-deficient (ZD) rats. We investigated whether apoptosis was involved in the reduction of NMBA-induced esophageal tumors when ZD rats consumed a zinc-suff...

2008
Maryke Steyn Andreas Roodt Gideon Steyl

In the title compound, [Zr(C(5)H(4)F(3)O(2))(4)]·C(7)H(8), the Zr atom is in a square-anti-prismatic coordination geometry that comprises four O,O'-bidentate trifluoro-acetyl-acetonate ligands. The O-Zr-O bite angles of the acetonate ligands range from 75.27 (5) to 75.41 (5)°. The Zr atom is located on a twofold rotation axis.

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