Bleomycin (BLM) biosynthesis has been studied as a model for hybrid peptide-polyketide natural product biosynthesis. Cloning, sequencing, and biochemical characterization of the blm biosynthetic gene cluster from Streptomyces verticillus ATCC15003 revealed that (1) the BLM hybrid peptide-polyketide aglycon is assembled by the BLM megasynthetase that consists of both nonribosomal peptide synthet...

This paper introduces an axiomatisation for equational hybrid logic based on previous axiomatizations and natural deduction systems for propositional and firstorder hybrid logic. Its soundness and completeness is discussed. This work is part of a broader research project on the development a general proof calculus for hybrid logics.

In the last decade, there has been a surge of interest in the problem of textual inference, which systems can use to automatically determine whether a hypothesis, H , can be inferred from a given text, T . A variety of approaches have been explored ranging from shallow-but-robust to deep-but-brittle. Systems that have tried to avoid semantic representations have applied shallow techniques on na...

I N nature, evolution is most likely taking place on the interpopulational level. Certain populations are better able to adapt to environmental changes than others. By comparing populations as a whole, one could attempt to find out what makes one population more successful in the evolutionary sense than another. BUZZATI-TRAVERSO ( 1952) emphasized this interpopulational problem when he stated t...

We present and evaluate several hybrid systems for sentiment identification for Twitter, both at the phrase and document (tweet) level. Our approach has been to use a novel combination of lexica, traditional NLP and deep learning features. We also analyse techniques based on syntactic parsing and tokenbased association to handle topic specific sentiment in subtask C. Our strategy has been to id...

Hybrid systems, i.e., dynamical systems combining discrete and continuous dynamics, have a complete axiomatization in differential dynamic logic relative to differential equations. Differential invariants are a natural induction principle for proving properties of the remaining differential equations. We study the equational case of differential invariants using a differential operator view. We...

We first give a coarse-grained modal-logical analysis of the four best known second-order false-belief tasks. This preliminary analysis shows that the four tasks share a common logical structure in which a crucial role is played by a “principle of inertia” which says that an agent’s belief is preserved over time unless the agent gets information to the contrary. It also reveals informational sy...

In Recent times, agriculture residue resembles sugarcane bagasse attracted the attention of researchers as it is considered a type reinforcement for polymeric composites used in industrial area. This study an attempt to utilize (natural fiber) hybridized with glass fiber (synthetic one fabricate new types hybrid composites. To obtain optimum mechanical properties, six different layering sequenc...

The complex process of allopolyploid speciation includes various mechanisms ranging from species crosses and hybrid genome doubling to genome alterations and the establishment of new allopolyploids as persisting natural entities. Currently, little is known about the genetic mechanisms that underlie hybrid genome doubling, despite the fact that natural allopolyploid formation is highly dependent...