BACKGROUND AND PURPOSE The location of intracerebral hemorrhage (ICH) is currently described in a qualitative way; we provide a quantitative framework for estimating ICH engagement and its relevance to stroke outcomes. METHODS We analyzed 111 patients with ICH from the Minimally Invasive Surgery Plus Recombinant-Tissue Plasminogen Activator for Intracerebral Evacuation (MISTIE) II clinical tr...

background:  the aim of this study was to evaluate whether higher serum levels of igf-i in the acute phase of ischemic stroke are associated with less severe strokes and better functional outcome in a period of one year follow up. methods: from october 2014 to august 2015, patients with the diagnosis of acute ischemic stroke admitted to the stroke unit of firoozgar hospital entered this prospec...

Background and purpose: Vitamin D deficiency has been shown to be linked to evolution of ischemic stroke, but the data regarding the association between stroke severity and vitamin D level is scarce. Materials and methods: Patients with first-ever acute ischemic stroke in the middle cerebral artery (MCA) territory within 7 days after the stroke were recruited. The control group included age an...

BACKGROUND AND PURPOSE Minor strokes and rapidly improving stroke symptoms are frequent exclusions for intravenous tissue-type plasminogen activator. We explored factors influencing tissue-type plasminogen activator treatment decision for minor strokes/rapidly improving stroke symptoms. METHODS A pilot survey, including 110 case scenarios, was completed by 17 clinicians from 2 academic medica...

BACKGROUND AND PURPOSE The use of intravenous thrombolysis is restricted to a minority of patients by the rigid 3-hour time window. This window may be extended by using modern imaging-based selection algorithms. We assessed safety and efficacy of MRI-based thrombolysis within and beyond 3 hours compared with standard CT-based thrombolysis. METHODS Five European stroke centers pooled the core ...

background: stroke is one of the most frequent causes of death and disability worldwide and has significant clinical and socioeconomic impact. hyperlipidemia and inflammation play major roles in atherothrombosis and in stroke. this study is conducted to compare the high sensitive c-reactive protein (hs-crp) levels and the lipid profile parameters between stroke patients and control group and de...

BACKGROUND AND RESEARCH OBJECTIVE Stroke is the primary cause of long-term disability among older adults. This study identifies predictors of functional independence and perceived stress for stroke survivors discharged home from inpatient rehabilitation with a spousal caregiver. SUBJECTS AND METHODS Stroke survivors (N = 97) were interviewed immediately after discharge to obtain scores on the...