Objectives: To demonstrate RxClass, a web interactive browser to explore the relationships between RxNorm drugs and drug classes from several sources including ATC, MeSH and NDF-RT. RxClass is publicly available at: http://mor.nlm.nih.gov/RxClass/ I. MOTIVATION Drug classes constitute important information about the drugs and are critical to important use cases, such as clinical decision suppor...

OBJECTIVES This analysis presents the prevalence of substance use among young adolescents. The extent to which factors such as peer behaviour, parenting practices and school commitment and achievement are associated with drinking to intoxication and other drug use is investigated. DATA SOURCE The data are from the 1998/99 National Longitudinal Survey of Children and Youth. Analysis is based o...

UNLABELLED BACKGROUND Structured Product Labeling (SPL) is a document markup standard approved by Health Level Seven (HL7) and adopted by United States Food and Drug Administration (FDA) as a mechanism for exchanging drug product information. The SPL drug labels contain rich information about FDA approved clinical drugs. However, the lack of linkage to standard drug ontologies hinders their ...

National and international publishers have been depositing digital publications at the National Library of the Netherlands (KB) since 2003. Until recently, most of these publications were deposited in the Portable Document Format. New projects, for example the web archiving project, force the KB to handle more heterogeneous material. Therefore, the KB has developed a quantifiable file format ri...

Background: An understanding of the patterns drug-resistant tuberculosis (DR-TB) is needed to develop best diagnostic tools and decide on optimal treatment combination therapies for management DR-TB in Nigeria. Objective: We aimed investigate five first-line anti-TB drugs over a period seven years (2010–2016) associated clinical socio-demographic factors. Methods: A retrospective study recruite...

Background and Aim: Cleaning and shaping is one of the important steps in endodontic treatment, which has an important role in root canal treatment outcome. This study evaluated the rate of file fracture and file deformation in Neolix rotary system and K-files in shaping of the mesiobuccal canal of maxillary first molars with moderate curvature.    Materials and Methods: In this ex vivo exp...

File system aging has been advocated for thorough analysis of any design, but it is cumbersome and often bypassed. Our aging study re-evaluates published file systems after aging using the same benchmarks originally used. We see significant performance degradation on HDDs and SSDs. With performance of aged file systems on SSDs dropping by as much as 80% relative to the recreated results of prio...