The plasmonic gold nanoparticles are promising candidates for photothermal therapy (PTT) application. The optical properties of various gold nanoparticles have been widely investigated for PTT application in the first near-infrared (NIR) window (650-950 nm). However, few studies have been reported on the nanoparticles employed in the second NIR window (1000-1350 nm) where light penetrates deepe...

Incorporation of compact spectroscopic near-infrared (NIR) light detectors into various wearable and handheld devices opens up new applications, such as on-the-spot medical diagnostics. To extend beyond the detection window silicon, i.e., past 1000 nm, organic semiconductors are highly attractive because their tunable absorption. In particular, NIR wavelength-selective have been realized by inc...

Therapeutic monitoring of immunosuppressive therapy with cyclosporine is a critical requirement because of intraand interpatient variability of drug absorption, narrow therapeutic window and drug induced nephrotox­ icity. The most widely used procedure involves measuring trough concen­ trations of cyclosporine (CsA) parent drug in whole blood using a specific monoclonal immunoassay. Trough conc...

Antifungal agents may be associated with significant toxicity or drug interactions leading to sub-therapeutic antifungal drug concentrations and poorer clinical outcomes for patients with haematological malignancy. These risks may be minimised by clinical assessment, laboratory monitoring, avoidance of particular drug combinations and dose modification. Specific measures, such as the optimal ti...

2D images of label-free biochips exploiting resonant waveguide grating (RWG) are presented. They indicate sensitivities on the order of 1 pg/mm2 for proteins in air, and hence 10 pg/mm2 in water can be safely expected. A 320x256 pixels Aluminum-Gallium-Nitride-based sensor array is used, with an intrinsic narrow spectral window centered at 280 nm. The additional role of characteristic biologica...

Single-walled carbon nanotubes (SWNTs) have a high optical absorbance in the near-infrared (NIR) region. In this special optical window, biological systems are known to be highly transparent. The optical properties of SWNTs provide an opportunity for selective photothermal therapy for cancer treatment. Specifically, CoMoCAT nanotubes with a uniform size (about 0.81 nm) and a narrow absorption p...