Being aware of the importance of statistical structure of poisonings for directing of toxicological analyses both in clinical and especially forensic medicine, the study was aimed at finding current incidence of narcotic substances intoxications in the Lower Silesia region of Poland as well as determining any long time trends. Data on causes of hospital admissions because of poisoning by narcot...

BACKGROUND Previous studies using linear regression analysis have shown that age, weight, gender, and the site of operation affect intravenous patient-controlled analgesia (IVPCA) narcotic use. However, there are inconsistent observations in the literature. The authors postulate that patient variables could have different effects at various doses of narcotics. To test this hypothesis, the autho...

PURPOSE It is difficult to balance adequate pain control against the risk of sedation and depressed breathing in severely obese patients. This study assesses the effects of combined preemptive and preventive analgesia on narcotic use after open gastric bypass. METHODS Twenty patients were randomized in this prospective double-blind trial comparing preoperative 30 mg intravenous ketorolac (Tor...

BACKGROUND In abdominal wall reconstruction, adequate pain control and minimization of narcotic consumption are essential to improving patient outcomes and satisfaction. Previous studies have examined the role of individual strategies, such as neuraxial analgesia and multimodal analgesia. However, there has not been a study that examined all potential determinants of postoperative narcotic requ...

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Deafferentation pain is known usually to be resistant to both narcotic and non-narcotic analgesics. Four cases of this condition are reported here in which benefit was obtained with pizotifen, a 5-hydroxytryptamine antagonist. Further controlled clinical studies are required to verify this observation.