We report the synthesis of tubular gold and silver nanoshells on silica nanowire core templates in solution. Silica nanowires were synthesized and characterized with optical and NMR methods. Gold nanoparticle seeds (2 to 3 nm) with weak repulsive surfactants such as tetrakis-hydroxymethyl-phosphonium chloride (THPC) were conjugated to the surface of these nanowires. A regrowth process was initi...

Au and Ag nanoshells are investigated as substrates for surface-enhanced Raman scattering (SERS). We find that SERS enhancements on nanoshell films are dramatically different from those observed on colloidal aggregates, specifically that the Raman enhancement follows the plasmon resonance of the individual nanoparticles. Comparative finite difference time domain calculations of fields at the su...

We demonstrate photothermal optical coherence tomography (OCT) imaging in highly scattering human breast tissue ex vivo. A 120 kHz axial scan rate, swept-source phase-sensitive OCT system at 1300 nm was used to detect phase changes induced by 830 nm photothermal excitation of gold nanoshells. Localized phase modulation was observed 300-600 microm deep in scattering tissue using an excitation po...

Using time-resolved pump-probe spectroscopy, we have performed the first investigation of the vibrational modes of gold nanoshells. The fundamental isotropic mode launched by a femtosecond pump pulse manifests itself in a pronounced time-domain modulation of the differential transmission probed at the frequency of nanoshell surface plasmon resonance. The modulation amplitude is significantly st...

3D ordered silver nanoshells silica photonic crystal beads as a novel encoded surface enhanced Raman scattering substrate are proposed for the development of highly efficient multiplex bioassays.

Saccharomyces cerevisiae yeast cells encapsulated with pH-responsive synthetic nanoshells from lightly cross-linked polymethacrylic acid showed a high viability rate of around 90%, an indication of high biocompatibility of synthetic pH-responsive shells. We demonstrated that increasing pH above the isoelectric point of the polymer shell leads to a delay in growth rate; however, it does not affe...

Nanoshells composed of close-packed silver nanocrystals have been fabricated on polystyrene spheres via direct electrostatic attraction at appropriate pH; the thickness and roughness of the shell can be readily controlled through a layer-by-layer technique.

Hollow nanoshells of layered double hydroxide (LDH) have been fabricated using exfoliated LDH nanosheets as a shell building block and polystyrene beads as a sacrificial template.