Tyrosinase has been immobilized on a Au nanoparticles encapsulated-dendrimer bonded conducting polymer on a glassy carbon electrode for the estimation of catechol. The modified electrode was characterized by cyclic voltammetry and AFM techniques. The principle of catechol estimation was based on the reduction of biocatalytically liberated quinone species at +0.2 V versus Ag/AgCl (3 M KCl), with...

We propose a nanosensor with a biological active part able to identify specific odorants. The biological part should be constituted by olfactory receptors pertaining to the G protein-coupled receptors, the most efficient natural sensors for odorant discrimination. Modeling, design, and experiments performed for proving the concept are reported and discussed.

Nanobiosensors can be built via functionalization of atomic force microscopy (AFM) tips with biomolecules capable of interacting with the analyte on a substrate, and the detection being performed by measuring the force between the immobilized biomolecule and the analyte. The optimization of such sensors may require multiple experiments to determine suitable experimental conditions for the immob...

Early diagnosis is the key to easy, low cost, and effective treatment of breast cancer. Therefore, studies have been accelerated identify cancer diagnostic biomarkers diagnose before it progresses. The use miR-155 as a potential biomarker in cancer, which has different levels at stages disease, provides simple serological test for prognosis/diagnosis, follow-up, treatment. Nanopolymers containi...

Semiconductor nanowire arrays offer significant potential for biosensing applications with optical read-out due to their high surface area and due to the unique optical properties of one-dimensional materials. A challenge for optical read-out of analyte-binding to the nanowires is the need to efficiently collect and detect light from a three-dimensional volume. Here we show that light from fluo...

In order to explore the clinical application of the nanobiosensor based on localized surface plasmon resonance (LSPR), we used our LSPR biosensor to detect the microalbuminuria in this work. The sliver nanoparticles were fabricated by using nanosphere lithography. The anti-human albumin antibody was immobilized on the sensor surface by amine coupling method. The different concentrations of comm...

Despite tremendous potential of highly sensitive electronic detection of biomolecules by nanoscale biosensors for genomics and proteomic applications, many aspects of experimentally observed sensor response (S) are difficult to understand within isolated theoretical frameworks of kinetic response or electrolyte screening. In this paper, we combine analytic solutions of Poisson-Boltzmann and dif...

In this study, a localized surface plasmon resonance (LSPR) nanobiosensor was designed to quantify anti-Brucella antibodies in the human sera. Smooth Lipopolysaccharide (LPS) extracted from Brucella melitensis via modified hot phenol water method and fixed on of gold nanoparticles by covalent interactions with functionalized nanoparticles. To obtain best performance probe, ratio LPS nanoparticl...