BACKGROUND Biotin has gained commercial popularity for its claimed benefits on healthy hair and nail growth. Despite its reputation, there is limited research to support the utility of biotin in healthy individuals. OBJECTIVE To systematically review the literature on biotin efficacy in hair and nail growth. METHODS We conducted a PubMed search of all case reports and randomized clinical tr...

The present study was to formulate a transungual drug delivery formulation. We targeted to formulate and evaluate fluconazole film for the nail fungal infection using extracted natural and evaluated penetration enhancer (PE). Model drug fluconazole was formulated with the natural extracted penetration enhancer with different ratios. The solvent for PE extraction was methanol and that extracts w...

Yellow nail syndrome is characterized by primary lymphoedema, recurrent pleural effusion and yellow discoloration of the nails. Although mechanical lymphatic obstruction is assumed to be the underlying pathology, it cannot explain the common finding of high albumin concentration in the pleural space. This paper describes a case of yellow nail syndrome presenting with the classical triad of lymp...

OBJECTIVE To evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis. DESIGN Open study involving 36 patients with moderate to severe nail psoriasis treated with acitretin. SETTING University-based outpatient dermatology clinic specializing in nail diseases. PATIENTS A total of 27 men and 9 women (mean age, 41 years) with nail psoriasis. INTERVENTION Ther...