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INTRODUCTION Leukoplakia is the most common potentially malignant condition of the oral cavity. AIM Epidemiological and clinical analysis of patients with oral leukoplakia (OL) diagnosed and treated in the Department of Maxillofacial and Oral Surgery, Medical University of Gdansk. MATERIAL AND METHODS The study was retrospective and prospective. Among 55 911 patients diagnosed and treated i...
Oral leukoplakia (OL) is a common, potentially malignant disorder of the oral cavity. SMAD4 was initially identified as a tumor suppressor and central mediator of transforming growth factor (TGF)-β signaling. In this study, we aimed to determine the expression patterns of SMAD4 in OL, its relationship with the degree of inflammation, and its clinical implications as a biomarker for OL malignant...
Learning of patterns by neural networks obeying general rules of sensory transductl and of converting membrane potentials to spiking frequencies is considered. A finite number of cells Ol can sample a pattern playing on any finite number of cells without causing irrevocable sampling bias if Ol = f:H or Ol () f:H = 1". Total eneJ transfer from inputs of Ol to outputs of f:H depends on the entrop...
BACKGROUND Terpinen-4-ol, a naturally occurring monoterpene is the main bioactive component of tea-tree oil and has been shown to have many biological activities. AIM To study the antitumor effects of terpinen-4-ol and its mechanism of action in prostate and GI malignancies, alone and in combination with chemotherapeutic and biological agents. METHODS Terpinen-4-ol was administrated alone o...
• Select stereo pair from data set, i.e. an original left view OL and an original right view OR (OL=8, OR=9) • Estimate depth corresponding to neighboring original views NL (left) and NR (right) (NL=7, NR=10), using any available camera • Synthesize views (synthesized left SL and synthesized right SR) at positions of OL and OR from NL+D and NR+D • Bring synthesized video to the meeting • Compar...
The article presents the results of collaborative study method for gas chromatographic determination alcoholic fermentation volatile by-products (acetaldehyde, methanol, methyl acetate, ethyl propan-2-ol, propan-1-ol, 2-methylpropan-1-ol, butan-1-ol, and 3-methylbutan-1-ol) in beverages with volume ethanol content a range 9.9–96.0% (wine, sake, liquor, tequila, vodka, grappa, bourbon, scotch, c...
A significant and increasing number of chronic kidney disease (CKD) patients are treated with online hemodiafiltration (OL-HDF), even in the absence of more conclusive survival data. OL-HDF affords several clinical benefits including control of anemia of CKD, a common affliction in dialysis patients. In efforts to understand the underlying mechanisms that contribute to the purported benefits of...
In the premature infant, hypoxic-ischemic damage to the cerebral white matter [periventricular leukomalacia (PVL)] is a common and leading cause of brain injury that often results in chronic neurologic disability from cerebral palsy. The cellular basis for the propensity of white matter injury to occur in the developing brain and the greater resistance of the adult white matter to similar injur...
The possibility that the serum concentrations of various cholesterol precursors may reflect the activity of the hepatic HMG-CoA reductase was investigated in humans under different conditions. The serum levels of squalene, free and esterified lanosterol, (4 alpha, 4 beta, 14 alpha-trimethyl-5 alpha-cholest-8, 24-dien-3 beta-ol), two dimethylsterols (4 alpha, 4 beta-dimethyl-5 beta-cholest-8-en-...
BACKGROUND Oleuropein (OL) is a well-known anti-oxidative agent and is shown to reduce the hypoxia-inducible factor 1 α (HIF1α) protein expression after radiation. The current study investigated the effects of OL on radiation response in nasopharyngeal carcinoma (NPC). METHODS Colony formation assay was performed to compare the radiation response in vitro. Xenograft mouse model was used to st...
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