Studies on the origin of bile pigment in normal man have revealed that a significant portion of bile pigment is derived from one or more sources other than the hemoglobin of mature, circulating erythrocytes (3). This finding suggested the possibility that the markedly increased quantities of bile pigment excreted in untreated pernicious anemia might also be derived in part from sources other th...

MicroRNAs (miRNAs), a class of small non-coding RNAs, recognize their mRNA targets based on perfect sequence complementarity. MiRNAs lead to broader changes in gene expression after plants are exposed to stress. High-throughput sequencing is an effective method to identify and profile small RNA populations in non-model plants under salt stresses, significantly improving our knowledge regarding ...

This study determined whether "living high-training low" (LHTL)-simulated altitude exposure increased the hypoxic ventilatory response (HVR) in well-trained endurance athletes. Thirty-three cyclists/triathletes were divided into three groups: 20 consecutive nights of hypoxic exposure (LHTLc, n = 12), 20 nights of intermittent hypoxic exposure (four 5-night blocks of hypoxia, each interspersed w...

In grassland ecosystems, N and P fertilization often increase plant productivity, but there is no concensus if fertilization affects soil C fractions. We tested effects of N, P and N+P fertilization at 5, 10, 15 g m-2 yr-1 (N5, N10, N15, P5, P10, P15, N5P5, N10P10, and N15P15) compared to unfertilized control on soil C, soil microbial biomass and functional diversity at the 0-20 cm and 20-40 cm...

Colorectal carcinomas (CRCs) with high-level microsatellite instability (MSI-H) often contain gene fusions, which involve receptor tyrosine kinases. This study included 105 MSI-H CRCs. NTRK1/2/3, ALK, ROS1 and RET fusions were analyzed by PCR test for 5’/3’-end unbalanced expression, is capable of detecting all translocation variants. The type rearrangements was subsequently determined variant-...

Given the high value of biochemical composition soybean seeds and versatility using this crop, need for it will continue to grow, which makes necessary improve existing develop new technologies its cultivation, considering local agroclimatic resources. Therefore, study, aiming investigate agroecological foundations use chemical biological techniques in modern growing soybeans, is relevant. The ...