Cytochrome P-450 and NADPH: cytochrome P-450 reductase were solubilized by detergents from microsomal fraction of tulip bulbs Tulipa fosteriana L. and purified to electrophoretic homogeneity. The purification was achieved by anion-exchange column chromatography, hydroxyapatite-column chromatography and affinity chromatography. The two enzyme showed relative molecular weights of about 54,200 and...

Carcinogenic azo dyes (dimethylaminoazobenzene, Sudan I) and N-nitrosamines (N-nitrosomethylaniline, N-nitrosomethylbenzylamine) are oxidized by cytochrome P-450 isoenzymes and peroxidase yielding metabolites which in vitro bind to DNA and transfer RNA (tRNA). The parallelism and differences in oxidative reactions are described. Peroxidase is more effective than P-450 in activating reactions of...

The carcinogenic effects of sequential treatment of female F344 rats with two nitrosamines were studied. The animals received either methylethylnitrosamine (NMEA), a strong liver carcinogen, N-nitrosomethylaniline (NMA), a moderately strong esophageal carcinogen, or N-nitrosopyrrolidine, (NPyr), a weaker liver carcinogen. The sequentially treated groups were given NMEA followed by NMA and vice ...

The title compound, C(21)H(19)NO, belongs to the family of α-amino-ketones. The structure contains three benzene rings, two of which [the phenyl ring in the 1-position (B) and the methylaniline ring (A)] are nearly coplanar [dihedral angle = 5.4 (1)°], whereas the phenyl ring in the 2-position (C) is nearly normal to them [dihedral angles = 81.8 (1) and 87.0 (1)° for A/C and B/C, respectively]....

Subcellular fractions from the avocado pear ( Persea americana) catalyzed formation of p-chloroaniline from p-chloro-N-methylaniline. Fractions prepared by centrifugation of avocado homogenates at 20, 000g for 20 min formed p-chloroaniline (2900 +/- 500 pmol min-1 mg protein-1) with an NADPH-generating system. p-Chloroaniline formation required reduced pyridine nucleotide (NADPH was 6-7 times m...

A library of metal oxide-conjugated polymer composites was prepared, encompassing WO3 -polyaniline (PANI), -poly(N-methylaniline) (PMANI), -poly(2-fluoroaniline) (PFANI), -polythiophene (PTh), -polyfuran (PFu) and -poly(3,4-ethylenedioxythiophene) (PEDOT) which were used as hole selective layers for perovskite solar cells (PSCs) fabrication. We adopted machine learning approaches to predict com...

Densities (ρ) speeds of sound (u) and viscosities (η) binary mixtures formamide (F) with aniline (A), N-methylaniline (NMA)and N,N-dimethylaniline (DMA), including those pure liquids, over the entire composition range were measured at temperatures (303.15, 308.15 313.15) K 0.1 MPa. Using experimental data, excess parameters (VE, ksE), deviation in viscosity (Δη), partial molar volumes, V¯m,1E V...