Polyacrylonitrile (PAN) gel was prepared by the freezing and thawing method using the solvents of N,N-dimethylacetamide (DMA) and tetramethylene sulfone(sulfolane). The gelation time after a series of freezing and thawing was examined with varying PAN concentration of DMA solution and the freezing time. Dynamic viscoelasticity was measured in the course of gelation for DMA solution to observe t...

polyimide/nickel oxide (polyimide/nio) nanocomposite was successfully synthesized by sol gel technique, using pyromellitic dianhydriede (pmda), 4,4-oxydianiline (oda) and n,n-dimethylacetamide (dmac) and 10 wt% nickel titanate nanopowders (nps). fourier transform infrared spectrometry (ftir), x-ray diffraction (xrd), scanning electron microscopy (sem), and vibrating sample magnetometer (vsm) we...

N,N-Dimethylacetamide (DMA) is a water-miscible solvent, FDA approved as excipient and therefore widely used as drug-delivery vehicle. As such, DMA should be devoid of any bioactivity. Here we report that DMA is epigenetically active since it binds bromodomains and inhibits osteoclastogenesis and inflammation. Moreover, DMA enhances bone regeneration in vivo. Therefore, our in vivo and in vitro...