نتایج جستجو برای: n acetyl cystein

تعداد نتایج: 990829  

2004
Young-Hee Kang Min-Jung Yi Min-Jung Kim Moon-Taek Park Sangwoo Bae Chang-Mo Kang Chul-Koo Cho In-Chul Park Myung-Jin Park Chang Hun Rhee Seok-Il Hong Hee Yong Chung Yun-Sil Lee Su-Jae Lee

Although mechanisms of arsenic trioxide (As2O3)-induced cell death have been studied extensively in hematologic cancers, those in solid cancers have yet to be clearly defined. In this study, we showed that the translocation of apoptosis-inducing factor (AIF) from mitochondria to the nucleus is required for As2O3-induced cell death in human cervical cancer cells. We also showed that reactive oxy...

2014
Seon-Mi Yu Song-Ja Kim

Withaferin A (WFA) is known as a constituent of Ayurvedic medicinal plant, Withania somnifera, and has been used for thousands of years. Although WFA has been used for the treatment of osteoarthritis (OA) and has a wide range of biochemical and pharmacologic activities, there are no findings suggesting its properties on chondrocytes or cartilage. The aim of the present study is to investigate t...

FABMS analysis of T-lb peptide before and after one cycle of Edman degradation indicated an unblocked N-terminal Thr residue for this tryptic peptide. In contrast , our data showed a molecular protonated ion, MH + for T- la peptide at 655 mass units (mu) which is 42 mu higher than the MH ion of T- 1b peptide. In addition, T- la peptide was not amenable to one cycle of manual Edman degrada...

Journal: :Acta Biochimica Polonica 1999

Journal: :Acta biochimica Polonica 2001
D Siodłak M A Broda B Rzeszotarska A E Kozioł I Dybała

Conformational preferences of Ac-deltaAla-NMe2 and Ac-(Z)-deltaPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.

Journal: :Journal of Biological Chemistry 1971

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