This paper reviews the available evidence concerning the side effects of atypical antipsychotics, including weight gain, type II diabetes mellitus, hyperlipidemia, QTc interval prolongation, myocarditis, sexual side effects, extrapyramidal side effects and cataract. Some rec­ ommendations about how to prevent and manage these side effects are also provided. It is concluded that atypical antipsy...

This paper takes as its starting point the assumption that the «Epidemiological Imagination» has a central role to play in the future development of policies and practice to improve population health and reduce health inequalities within and between states but suggests that by neglecting the contribution that qualitative research can make epidemiology is failing to deliver this potential. The p...

Context: Cadmium oxide nanoparticles (CdO NPs) are employed in optoelectronic devices and as a starting material for generating quantum dots as well as for medical imaging and targeting of pharmaceutical agents to disease sites. However, there are lack of data concerning shortand long-term effects of CdO NPs on the lungs. Objective: To determine the effects of inhaled CdO NPs at an occupational...

t sounds like a paradox, but there is only one real trend evident in today's global market, and that is continuous – and rapid – change. The market environment is uncertain; competitors are changing; new, disruptive technologies are emerging; and topping all this, customers are becoming more demanding. To be successful in such a dynamic market, globally operating companies must be able to suppl...

PURPOSE Cervical cytology and human papillomavirus (HPV) DNA co-testing is recommended as a screening method for detecting cervical lesions. However, for women who are HPV-positive but cytology-negative, the appropriate management and significance of HPV-58 infection remain unknown. METHODS This study of prevalent HPV detected at baseline with a median follow-up of 3.2 years evaluated the ris...

We have shown recently that estrogen receptor (ER) ligands share a diphenyl ethane pharmacophore with Sah 58-035 [3-[decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenylethyl]-propanamide], a prototypical inhibitor of the acyl-cholesterolacyl-transferase (ACAT), which enabled us to establish that ER ligands were potent inhibitors of ACAT and blocked the formation of foam cells. In the present stu...