A child with many symptoms of trisomy 22 syndrome is described. The child showed a 46,XY/47,XY,+22 chromosome constitution. This is the first reported case of a trisome 22 phenotype with such a mosaic karyotype.

The two-user linear deterministic interference channel (LDIC) with noisy channel-output feedback is fully described by six parameters that correspond to the number of bit-pipes between each transmitter and its corresponding intended receiver, i.e., −→n 11 and −→n 22; between each transmitter and its corresponding non-intended receiver i.e., n12 and n21; and between each receiver and its corresp...

Four randomised controlled trials (RCTs) and one RCT metaanalysis are featured in the Journal this month. The latter is a review of trials of newer-generation antidepressants and cognitive–behavioural therapy (CBT) for adolescent depression (Dubicka et al, pp. 433–440). In an area of clinical practice plagued by controversy, the authors of this review were able to contribute the finding that ad...

The thermal radiation from small, laser heated, positively charged niobium clusters has been measured. The emitted power was determined by the quenching effect on the metastable decay, employing two different experimental protocols. The radiative power decreases slightly with cluster size and shows no strong size-to-size variations. The magnitude is 40-50 keV/s at the timescale of several micro...

We report a family with co-occurring disorders including neuroblastoma in the first child conceived by in-vitro fertilization with history of sodium valproate use by the mother during pregnancy and mosaic trisomy 22 in the third child. We discuss the possibility of an association between the disorders but conclude that no firm aetiological connection can be established between the different dis...

We present a joint theoretical and experimental investigation of the absorption spectra of silver clusters Ag(n) (4<or=n<or=22). The experimental spectra of clusters isolated in an Ar matrix are compared with the calculated ones in the framework of the time-dependent density functional theory. The analysis of the molecular transitions indicates that the s-electrons are responsible for the optic...

Three papers in the Journal this month consider issues related to measuring, understanding and treating mental ill health in childhood. Baron-Cohen et al (pp. 500–509) undertook a study to establish the prevalence of autism-spectrum conditions in Cambridgeshire using two case ascertainment methods. First, a survey of individuals on the Special Educational Needs register and second, a screening ...