Type 2 diabetes mellitus is among the most powerful independent risk factors of the cardiovascular disease presence and is associated with a 3 to 5× higher cardiovascular event risk. This has long been recognized by the National Cholesterol Education Program report in the United States and European guidelines, both labeling type 2 diabetes mellitus a coronary artery disease (CAD) equivalent. Al...

RESEARCH DESIGN AND METHODSdWe examined 1,275 stable patients with diabetes mellitus undergoing elective diagnostic coronary angiography with cardiac troponin I (cTnI) levels below the diagnostic cut-off for defining myocardial infarction (,0.03 ng/mL). The relationship of subclinical myocardial necrosis (cTnI 0.009–0.029 ng/mL) with incident major adverse cardiovascular events (MACE; defined a...

Diabetes mellitus, the metabolic syndrome, and the underlying insulin resistance are increasingly associated with diastolic dysfunction and reduced stress tolerance. The poor prognosis associated with heart failure in patients with diabetes after myocardial infarction is likely attributable to many factors, important among which is the metabolic impact from insulin resistance and hyperglycemia ...

UNLABELLED Stress myocardial perfusion imaging is a useful method for evaluation of coronary artery disease (CAD) in patients with diabetes mellitus. However, its role in predicting all-cause mortality is not well defined. The aim of this study was to determine whether myocardial ischemia on stress myocardial perfusion imaging can predict all causes of death in patients with diabetes mellitus. ...

Introduction The correlations between chronic kidney disease (CKD) and atherosclerotic disease include both early onset and severe evolution of the atherosclerotic lessions, as well as a higher risk for acute cardiovascular events (Levey et al 1998). The high prevalence and severity of atherosclerotic lessions in patients with CKD, is explained by the often cumulative presence of hypertension, ...

BACKGROUND Yantai is a developed medium-sized coastal city in Eastern China, having a population of 1.6845 million. With the development of economy, some middle-aged and adolescent people (< 45 years) devote themselves to work and suffer from greater stress, which makes them ignore their own health. Moreover, they have unhealthy lifestyles and lack the knowledge of cardiovascular risk factors. ...

Recent years have seen the seemingly unstoppable attack by cardiologists on all diseases that limit cardiovascular health. Nowhere is this more evident than in the case of diabetes mellitus, the subject of an important article in this issue of Circulation1 that relates to renoprotection in type 2 diabetes mellitus. As a background, type 2 diabetes is increasing in incidence and cardiological si...

BACKGROUND There is growing evidence of an association between oral health, specifically dental status, and chronic systemic diseases. However, varying measures of dental status across different populations and low study sample has made comparison of studies and conclusion of findings unclear. Our aim is to examine whether the number of teeth as a measure of dental status is associated with inc...

We present the case of a 65-year-old man with type 2 diabetes mellitus, arterial hypertension, hypercholesterolemia, salicylate allergy and diagnosed ischemic heart disease since 2000. The patient, despite intensive pharmacotherapy according to European Society Cardiology guidelines insertion as many 11 stents into coronary arteries, had persistent recurrent acute syndromes, including 4 myocard...

BACKGROUND A prior diagnosis of diabetes mellitus is associated with adverse outcomes after acute myocardial infarction (MI), but the risk associated with a new diagnosis of diabetes in this setting has not been well defined. METHODS AND RESULTS We assessed the risk of death and major cardiovascular events associated with previously known and newly diagnosed diabetes by studying 14,703 patien...