نتایج جستجو برای: myocardial infarct size
تعداد نتایج: 710656 فیلتر نتایج به سال:
OBJECTIVE We studied the effect of the angiotensin II type 1 (AT1)-receptor antagonist candesartan on infarct size resulting from regional myocardial ischemia in pigs. BACKGROUND The effects of AT1-receptor blockade on infarct size in different species remain controversial and its potential cardioprotective mechanisms are still unclear. In pigs, infarct development closely resembles that obse...
BACKGROUND A cardioprotective role of morphine acting via opioid receptors has been demonstrated, and previous preclinical studies have reported that morphine could reduce reperfusion injury and myocardial infarct size in a way similar to that of ischemic periconditioning. This study aimed to evaluate the effect of intracoronary morphine on myocardial infarct size in patients with ST-elevation ...
BACKGROUND Infarct size is a strong predictor of mortality and major adverse cardiovascular events after myocardial infarction. Acute reperfusion therapy limits infarct size and improves survival, but its use has been confined to patients with ST-segment-elevation myocardial infarction. The purpose of this study was to assess the relationship between echocardiographic parameters of left ventric...
Hypothermia has proven to be one of the most potent and consistent adjunctive therapies for infarct size reduction in numerous preclinical studies, when administered prior to reperfusion. The mechanisms leading to protection are multifactorial. Early clinical trials failed to demonstrate a decrease in infarct size, likely due to the difficulty in achieving adequate cooling prior to reperfusion....
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