نتایج جستجو برای: mus musculus

تعداد نتایج: 5849  

2016
Bettina Harr Emre Karakoc Rafik Neme Meike Teschke Christine Pfeifle Željka Pezer Hiba Babiker Miriam Linnenbrink Inka Montero Rick Scavetta Mohammad Reza Abai Marta Puente Molins Mathias Schlegel Rainer G Ulrich Janine Altmüller Marek Franitza Anna Büntge Sven Künzel Diethard Tautz

Wild populations of the house mouse (Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology. We provide whole genome sequencing data of individuals representing natural populations of M. m. domesticus (24 individuals from 3 populations), M. m. helgolandicus (3 individuals), M. m. musculus (22...

Journal: :Journal of virology 2013
Carrie Martin Alicia Buckler-White Kurt Wollenberg Christine A Kozak

Xenotropic mouse leukemia viruses (X-MLVs) are broadly infectious for mammals except most of the classical strains of laboratory mice. These gammaretroviruses rely on the XPR1 receptor for entry, and the unique resistance of laboratory mice is due to two mutations in different putative XPR1 extracellular loops. Cells from avian species differ in susceptibility to X-MLVs, and 2 replacement mutat...

Journal: :Molecular biology and evolution 1988
H Yonekawa K Moriwaki O Gotoh N Miyashita Y Matsushima L M Shi W S Cho X L Zhen Y Tagashira

The Japanese mouse, Mus musculus molossinus, has long been considered an independent subspecies of the house mouse. A survey of restriction-site haplotypes of mitochondrial DNA (mtDNA) showed that Japanese mice have two main maternal lineages. The most common haplotype is closely related to the mtDNA of the European subspecies M. m. musculus. The other common haplotype and two minor ones are cl...

Journal: :Proceedings. Biological sciences 2014
Yasmin Latour Marco Perriat-Sanguinet Pierre Caminade Pierre Boursot Carole M Smadja Guila Ganem

Sexual selection may hinder gene flow across contact zones when hybrid recognition signals are discriminated against. We tested this hypothesis in a unimodal hybrid zone between Mus musculus musculus and Mus musculus domesticus where a pattern of reinforcement was described and lower hybrid fitness documented. We presented mice from the border of the hybrid zone with a choice between opposite s...

Journal: :Cancer research 1981
D Colcher P Horan Hand Y A Teramoto D Wunderlich J Schlom

Monoclonal antibodies have been generated against disrupted mammary tumor viruses isolated from Mus musculus, Mus cervicolor, and Mus cookii. Monoclonal antibodies directed against the M.W. 36,000 external glycoproteins of these viruses demonstrate the presence of multiple epitopes, i.e., distinct antigenic determinants, within these glycoproteins. These epitopes represent type, group, and inte...

Journal: :Molecular biology and evolution 1988
C Delarbre Y Kashi P Boursot J S Beckmann P Kourilsky F Bonhomme G Gachelin

We have examined the phylogenetic distribution of two t-specific markers among representatives of various taxa belonging to the genus Mus. The centromeric TCP-1a marker (a testicular protein variant specific for all t-haplotypes so far studied) has also been apparently detected in several non-t representatives of the Mus IVA, Mus IVB, and probably M. cervicolor species. By contrast, a t-specifi...

2018
Sankar Subramanian

The ratio of diversities at amino acid changing (nonsynonymous) and neutral (synonymous) sites (ω = πN/πS) is routinely used to measure the intensity of selection pressure. It is well known that this ratio is influenced by the effective population size (Ne) and selection coefficient (s). Here, we examined the effects of effective population size on ω by comparing protein-coding genes from Mus m...

Journal: :Molecular biology and evolution 1994
Y Nishioka B M Dolan L Zahed V Prado H Tyson

A 522-base-long Y-chromosomal sequence was isolated from a BALB/c genomic library and was designated "BF046." It is repeated about 200 times in the male genome, and a difference was detected between the Mus musculus musculus and the M. m. domesticus type Y chromosomes. BF046-related sequences were present over the entire length of the Y chromosome as visualized by in situ hybridization. Souther...

Journal: :Genetics 1986
Y Nishioka E Lamothe

The Y chromosome plays a dominant role in mammalian sex determination, and characterization of this chromosome is essential to understand the mechanism responsible for testicular differentiation. Male mouse genomic DNA fragments, cloned into pBR322, were screened for the presence of Bkm (a female snake satellite DNA)-related sequences, and we obtained a clone (AC11) having a DNA fragment from t...

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