Nitroxide spin labels are used for double electron-electron resonance (DEER) measurements of distances between sites in biomolecules. Rotation of gem-dimethyls in commonly used nitroxides causes spin echo dephasing times (Tm) to be too short to perform DEER measurements at temperatures between ∼80 and 295 K, even in immobilized samples. A spirocyclohexyl spin label has been prepared that has lo...

Early promoter activity of HPV-58 molecular variants isolated from high-grade cervical lesions in Brazil was compared. Luciferase reporter assays were conducted in C33 cells transfected with the complete long control region of 3 molecular variants of HPV-58 as well as HPV-58, -18 or -16 prototypes. The HPV-58 prototype and Bsb-329 and Bsb-367 variants showed a promoter activity similar to that ...

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, 227a (2002); 295 Science et al. Pieter R. Roelfsema, Do Neurons Predict the Future? www.sciencemag.org (this information is current as of April 14, 2008 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/295/5553/227a version of this article at: including high-resolution figures, can be found in the online Updated information ...

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This study has demonstrated a rapid spectroscopic method for the determination of chlorine dioxide and hypochlorous acid concentrations in the pulp bleaching processes. It was found that chlorine dioxide and hypochlorous acid have an isosbestic wavelength of 295 nm. The soluble lignin in such a system is the main interference, but can be corrected by determining the absorbances at 295 nm, 380 n...

We compared the expression levels of 307 miRNAs in six different B16F1 melanoma cell lines of differing malignant properties and found that the miR-290-295 cluster showed a strong upregulation in the more malignant B16F1 daughter cell lines. Its overexpression in B16F1 cells had no major effects on cell proliferation, migration or anchorage-independent growth, but conferred resistance to glucos...

L. Z. Shi, Q. Zhu, T. Wu, M. L. Duquette, V. Gomez, C. Chandsawangbhuwana, M. S. Harsono, N. Hyun, N. Baker, J. Nascimento, Z. You, E. B. Botvinick and M. W. Berns Institute of Engineering in Medicine, University of California, San Diego, 9500 Gilman Dr. SERF 295, MC 0435 La Jolla, CA 92093, USA Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 926...