how to cite this article: najafi mr, najafi ma, nasr z. diagnosis and management of multiple sclerosis in children. iran j child neurol. summer 2016; 10(3): 13-23. abstract growing evidence indicates the safety and well toleration of treatment by disease-modifying in children suffering multiple sclerosis (ms). the treatment is not straight forward in a great number of patients, thus patients wi...

background: there have  been  several studies  done  on the role of metals in the occurrence  of multiple sclerosis (ms) disease, but their roles have not been confirmed yet. because of the lack of information on this issue, this study compared  the  serum  level  of  copper and zinc in ms patients with their levels in a control group. methods: this  was  an  analytical,  cross-sectional  study...

multiple  sclerosis  (ms) is  an  autoimmune  multifactorial  degenerative  disease  with detrimental affliction on central nervous system. mhc class i chain- related genea,b(mica and micb) are nonclassical human leukocyte antigens that can affect on some diseases and also on transplantation. the purpose of this study was to evaluate the mica and micb mrna expression in multiple sclerosis patie...

multiple sclerosis (ms) is an inflammatory disorder, in which neurons in central nervous system (cns) become demyelinated .ms is named for its formation of plaques due to sclerosis of myelin. variable degree of demyelination results in mild, mediate or severe symptomatic episodes of this disease. it is commonly characterized by recurrent relapses and often followed by severe neurological disabi...

patients and methods in this study, a total of 92 patients with relapsing-remitting multiple sclerosis (rrms) were randomly allocated into three equal groups; each treatment group received one of the foregoing drugs (cinnovexr, rebif and betaferon) for one year. at the beginning and end of the study, patients ‘ edss was measured and compared. results in this study, the relative frequency of fem...

abstract introduction:  this study was performed to compare the effects of low-dose interferon beta-1(cinnovex,30 mcg) and high-dose interferon beta-1(rebif,44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (mri) in patients with multiple sclerosis (ms). methods and materials: this historical cohort study, which was performed in 2014 in sanandaj (western p...

from september 18th - 20th, 2015, the 1st international razavi multiple sclerosis congress was held in mashhad, iran. the meeting was designated as a platform especially for young scientists to get internationally connected, discuss recent scientific findings and develop further ideas for strategic collaborations between germany and iran. physicians and scientists from research groups working i...